Recent advancement of HDAC inhibitors against breast cancer
SA Mehmood, KK Sahu, S Sengupta, S Partap… - Medical Oncology, 2023 - Springer
Recent studies highlight the great potential impact of HDAC inhibitors (HDACis) in
suppressing TNBC, even though clinical trials including a single HDACis demonstrated …
suppressing TNBC, even though clinical trials including a single HDACis demonstrated …
Himalayan flora: targeting various molecular pathways in lung cancer
A James, K Akash, A Sharma, S Bhattacharyya… - Medical Oncology, 2023 - Springer
The fatal amplification of lung cancer across the globe and the limitations of current
treatment strategies emphasize the necessity for substitute therapeutics. The incorporation …
treatment strategies emphasize the necessity for substitute therapeutics. The incorporation …
Matrine mediated neuroprotective potential in experimental multiple sclerosis: evidence from CSF, blood markers, brain samples and in-silico investigations
Multiple sclerosis (MS) is a debilitating, inflammatory, and demyelinating disease of the
central nervous system influenced by environmental and genetic factors. Around 2.8 million …
central nervous system influenced by environmental and genetic factors. Around 2.8 million …
Melatonin-mediated IGF-1/GLP-1 activation in experimental OCD rats: evidence from CSF, blood plasma, brain and in-silico investigations
Obsessive-compulsive disorder (OCD) is a neuropsychiatric condition characterized by
intrusive, repetitive thoughts and behaviors. Our study uses a validated 8-OH-DPAT-induced …
intrusive, repetitive thoughts and behaviors. Our study uses a validated 8-OH-DPAT-induced …
[PDF][PDF] Icariin prevents methylmercury-induced experimental neurotoxicity: Evidence from cerebrospinal fluid, blood plasma, brain samples, and in-silico investigations
Abstract Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease that
causes significant neurodegeneration. Methylmercury (MeHg+) is a neurotoxin that induces …
causes significant neurodegeneration. Methylmercury (MeHg+) is a neurotoxin that induces …
Exploration of antiproliferative potential of modified triazole–benzohydrazone scaffold: Multitarget approach
A novel series of triazole–benzohydrazone hybrids was efficiently designed and synthesized
as antiproliferative agents, targeting different kinases. All compounds were screened via the …
as antiproliferative agents, targeting different kinases. All compounds were screened via the …
Network pharmacological analysis and experimental study of cucurbitacin B in oral squamous cell carcinoma
Z Yu, S Liang, L Ji, YH Cheng, W Yan, R Gao… - Molecular Diversity, 2023 - Springer
Oral squamous cell carcinoma (OSCC) is a malignant tumor with a high incidence and poor
prognosis. Cucurbitacin B (CuB) is a tetracyclic triterpenoid small-molecule compound …
prognosis. Cucurbitacin B (CuB) is a tetracyclic triterpenoid small-molecule compound …
N‐Hydroxyalkanamide Based Organo/hydrogels as Novel Scaffolds for pH‐Dependent Metronidazole and Theophylline Release
The traditional delivery of metronidazole and theophylline presents challenges like bitter
taste, variable absorption, and side effects. However, gel‐based systems offer advantages …
taste, variable absorption, and side effects. However, gel‐based systems offer advantages …