Importance Intravenous thrombolysis with tenecteplase improves reperfusion prior to
endovascular thrombectomy for ischemic stroke compared with alteplase. Objective To …

Importance DL-3-n-butylphthalide (NBP) is a drug for treating acute ischemic stroke and may
play a neuroprotective role by acting on multiple active targets. The efficacy of NBP in …

Background and Purpose—The modified Rankin Scale (mRS) at 3 months is the most
commonly used primary outcome measure in stroke treatment trials, but it lacks specificity …

Importance General anesthesia during thrombectomy for acute ischemic stroke has been
associated with poor neurological outcome in nonrandomized studies. Three single-center …

Importance The efficacy and safety of endovascular thrombectomy (EVT) in patients with
large ischemic cores remains unknown, to our knowledge. Objective To compare outcomes …

Background and Purpose: Available data on the clinical course of patients with acute
ischemic stroke due to medium vessel occlusion (MeVO) are mostly limited to those with M2 …

Importance The efficacy of endovascular thrombectomy (EVT) for symptomatic large anterior
vessel occlusion (sLAVO) sharply decreases with time. Because EVT is restricted to …

Importance Mechanical thrombectomy (MT) improves clinical outcomes in patients with
acute ischemic stroke (AIS) caused by a large vessel occlusion. However, it is not known …

According to Alzheimer's Disease International, 55 million people worldwide are living with
dementia. Dementia is a disorder that manifests as a set of related symptoms, which usually …

Importance Endovascular therapy (EVT) has been found to reduce functional disability in
patients with acute stroke due to large-vessel occlusion. However, the extent of the ischemic …