The development of therapeutic cancer vaccines as a means to generate immune reactivity
against tumors has been explored since the early discovery of tumor-specific antigens by …

Although the earliest—rudimentary—attempts at exploiting the immune system for cancer
therapy can be traced back to the late 18th Century, it was not until the past decade that …

The purpose of the present study was to identify an “easy-to-adopt” strategy to enhance
immune responses using functionalized alginate (ALG) nanoparticles (MAN-ALG/ALG= OVA …

Identification of biomarkers is essential for diagnosis, targeted therapy and prognosis
evaluation of diseases, especially cancers. Currently, the number of ideal clinical …

Simple Summary Cancer immunotherapy has now attracted much attention because of the
recent success of immune checkpoint inhibitors. However, they are only beneficial in a …

Cancer immunity is dependent on dynamic interactions between T cells and dendritic cells
(DCs). Polymer-based nanoparticles target DC receptors to improve anticancer immune …

Background The aim of this study was to explore the feasibility of delivering tumor antigens
and enhancing the antigen cross-presentation of dendritic cells (DCs) by aluminum …

Dendritic cell (DCs) are essential antigen processing and presentation cells that play a key
role in the immune response. In this study, DCs were co‑cultured with cytokine‑induced killer …

Multiple myeloma (MM) is closely dependent on cross-talk between malignant plasma cells
and cellular components of the inflammatory/immunosuppressive bone marrow milieu …

Opinion statement The primary objective of this study is to evaluate the effectiveness of
cancer vaccines containing genetically modified dendritic cells (DCs) in inducing …