Cancers, like other diseases, arise from gene mutations and/or altered gene expression,
which eventually cause dysregulation of numerous proteins and noncoding RNAs. Changes …

Although gastric cancer (GC) is highly prevalent in China and is a leading cause of cancer-
related death, major advances in early diagnostic and effective therapeutic strategies have …

Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive form of non-
Hodgkin lymphoma with variable biology and clinical behavior. The current classification …

Genetic polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) enzyme may
influence DNA methylation. Alterations in DNA methylation patterns of genes involved in the …

Gastric cancer (GC) is one of the most frequently diagnosed malignancies in East Asia,
particularly in China, and remains the second leading cause of cancer‑associated mortality …

Background: Aberrant promoter hypermethylation has been recognized in human breast
carcinogenesis as a frequent molecular alteration associated with the loss of expression of a …

The silencing of the tumor suppressor gene O-6-methylguanine-DNA methyltransferase
(MGMT) by promoter methylation commonly occurs in human cancers. The relationship …

Gastric cancer (GC) is one of the most common cancers and the second leading cause of
cancer-related mortality. Increasing discoveries have highlighted aberrant epigetic …

Background: Promoter hypermethylation is a common event in human cancer. O6-
methylguanine-DNA methyltransferase (MGMT) is a gene involved in DNA repair, which is …

Background/Aims: Human mutL homolog 1 (MLH1) promoter methylation was reported in
gastric cancer (GC). This study determined the clinicopathological, prognostic, and …