One of the major challenges that remain in the fields of aging and lifespan determination
concerns the precise roles that reactive oxygen species (ROS) play in these processes …

Aging clocks have provided one of the most important recent breakthroughs in the biology of
aging, and may provide indicators for the effectiveness of interventions in the aging process …

Aging is a ubiquitous biological process that limits the maximal lifespan of most organisms.
Significant efforts by many groups have identified mechanisms that, when triggered by …

Naringin is a dihydroflavonoid, which is rich in several plant species used for herbal
medicine. It has a wide range of biological activities, including antineoplastic, anti …

Mild impairment of mitochondrial function has been shown to increase lifespan in genetic
model organisms including worms, flies and mice. To better understand the mechanisms …

An imbalance in cellular homeostasis occurring as a result of protein misfolding and
aggregation contributes to the pathogeneses of neurodegenerative diseases, including …

How animals rewire cellular programs to survive cold is a fascinating problem with potential
biomedical implications, ranging from emergency medicine to space travel. Studying a …

Bioluminescence microscopy is an appealing alternative to fluorescence microscopy,
because it does not depend on external illumination, and consequently does neither …

The aging process deteriorates organs' function at different levels, causing its progressive
decline to resist stress, damage, and disease. In addition to alterations in metabolic control …

Mitochondria take part in a network of intracellular processes that regulate homeostasis.
Defects in mitochondrial function are key pathophysiological changes during AKI. Although …