The maintenance of proteostasis is essential for cellular and organism healthspan. How
proteostasis collapse influences reproductive span remains largely unclear. In …

The adult nervous system has a limited capacity to regenerate after accidental damage. Post-
injury functional restoration requires proper targeting of the injured axon to its postsynaptic …

Background Large-scale production and application of amorphous silica nanoparticles
(SiNPs) have enhanced the risk of human exposure to SiNPs. However, the toxic effects and …

We have reported recently that submaximal inhibition of the Sarco Endoplasmic Reticulum
Ca 2+ ATPase (SERCA) produces an increase in the lifespan of C. elegans worms. We have …

Studies in Caenorhabditis elegans have revealed that even a genetically identical
population of animals exposed to the same environment displays a remarkable level of …

Background Campylobacter jejuni is the major micro-bacillary pathogen responsible for
human coloenteritis. Lactic acid bacteria (LAB) have been shown to protect against …

Hyperinfection and disseminated infection by the parasitic nematode Strongyloides
stercoralis can be induced by iatrogenic administration of steroids and immunosuppression …

Cells engage complex surveillance mechanisms to maintain mitochondrial function and
protein homeostasis. LonP1 protease is a key component of mitochondrial quality control …

Maize is the food crop with the highest total output in the world. However, corn bran is only a
by‐product with low price. The 5, 5′‐diferulic acid glucoside esters (DFG) were obtained …

Mutations that result in a mild impairment of mitochondrial function can extend longevity.
Previous studies have shown that the increase in lifespan is dependent on stress responsive …