Global colistin use: a review of the emergence of resistant Enterobacterales and the impact on their genetic basis

U Binsker, A Käsbohrer… - FEMS Microbiology …, 2022 - academic.oup.com
The dramatic global rise of MDR and XDR Enterobacterales in human medicine forced
clinicians to the reintroduction of colistin as last-resort drug. Meanwhile, colistin is used in …

Mobile Colistin Resistance (mcr) Gene-Containing Organisms in Poultry Sector in Low- and Middle-Income Countries: Epidemiology, Characteristics, and One Health …

MU Anyanwu, IF Jaja, COR Okpala, EO Njoga… - Antibiotics, 2023 - mdpi.com
Mobile colistin resistance (mcr) genes (mcr-1 to mcr-10) are plasmid-encoded genes that
threaten the clinical utility of colistin (COL), one of the highest-priority critically important …

Polymyxin resistance in Enterobacterales: overview and epidemiology in the Americas

J Rodríguez-Santiago, P Cornejo-Juárez… - International Journal of …, 2021 - Elsevier
The worldwide spread of carbapenem-and polymyxin-resistant Enterobacterales represents
an urgent public-health threat. However, for most countries in the Americas, the available …

Mobile Colistin Resistance (mcr) Genes in Cats and Dogs and Their Zoonotic Transmission Risks

A Hamame, B Davoust, Z Cherak, JM Rolain, SM Diene - Pathogens, 2022 - mdpi.com
Background: Pets, especially cats and dogs, represent a great potential for zoonotic
transmission, leading to major health problems. The purpose of this systematic review was …

Antimicrobial resistance surveillance of Escherichia coli from chickens in the Qinghai Plateau of China

B Tang, J Wang, X Zheng, J Chang, J Ma… - Frontiers in …, 2022 - frontiersin.org
Antimicrobial resistance (AMR) may lead to worldwide epidemics through human activities
and natural transmission, posing a global public safety threat. Colistin resistance mediated …

Human colonization with antibiotic-resistant bacteria from nonoccupational exposure to domesticated animals in low-and middle-income countries: a critical review

JM Swarthout, EMG Chan, D Garcia… - Environmental …, 2022 - ACS Publications
Data on community-acquired antibiotic-resistant bacterial infections are particularly sparse
in low-and middle-income countries (LMICs). Limited surveillance and oversight of antibiotic …

[HTML][HTML] mcr-1 colistin resistance gene sharing between Escherichia coli from cohabiting dogs and humans, Lisbon, Portugal, 2018 to 2020

J Menezes, JM da Silva, SM Frosini, A Loeffler… - …, 2022 - eurosurveillance.org
Background The emergence of colistin resistance is a One Health antimicrobial resistance
challenge worldwide. The close contact between companion animals and humans creates …

mcr-1 Gene in Latin America: How Is It Disseminated Among Humans, Animals, and the Environment?

SAM Lentz, TV Dalmolin, AL Barth… - Frontiers in Public …, 2021 - frontiersin.org
In the last decade, polymyxins have been reintroduced in the therapeutic arsenal to treat
severe infections by carbapenem-resistant Enterobacterales. At that time, reports of …

Removal of Extended-Spectrum Beta-Lactamase-Producing Escherichia coli, ST98, in Water for Human Consumption by Black Ceramic Water Filters in Low-Income …

C Bastidas-Caldes, J Ochoa… - International Journal of …, 2022 - mdpi.com
Fecal contamination in natural water sources is a common problem in low-income countries.
Several health risks are associated with unprotected water sources, such as gastrointestinal …

[HTML][HTML] Comparative Genomics of Three Hybrid-Pathogen Multidrug-Resistant Escherichia coli Strains Isolated from Healthy Donors' Feces

JZ Ortega-Enríquez, C Martínez-de la Peña… - Microbiology …, 2024 - mdpi.com
The present study shows the genomic characterization of three pathogenic Escherichia coli
hybrid strains. All strains were previously characterized as diarrheagenic pathotypes (DEC) …