Throughout the body, lymphatic fluid movement supports critical functions including
clearance of excess fluid and metabolic waste. The glymphatic system is the analog of the …

The human brain contains more than 100 trillion (1014) synaptic connections, which form all
of its neural circuits. Neuroscientists have long been interested in how this complex synaptic …

Diffusion in the extracellular space (ECS) of the brain is constrained by the volume fraction
and the tortuosity and a modified diffusion equation represents the transport behavior of …

As exemplified particularly with vasopressin and oxytocin, release of neuropeptides within
the brain occurs from dendrites, somata, and axons of neurosecretory neurons; mechanisms …

The NMDA receptor is a key player in excitatory transmission and synaptic plasticity in the
central nervous system. Its activation requires the binding of both glutamate and a coagonist …

The function and efficacy of synaptic transmission are determined not only by the
composition and activity of pre‐and postsynaptic components but also by the environment in …

Analysis of excitatory synaptic transmission in the rat hypothalamic supraoptic nucleus
revealed that glutamate clearance and, as a consequence, glutamate concentration and …

Glutamate is the principal excitatory neurotransmitter of the central nervous system, but
many studies have expanded its functional repertoire by showing that glutamate receptors …

Nearly one‐half of the cells in a human brain are astrocytes, but the function of these little
cells remains a great mystery. Astrocytes form an intimate association with synapses …

The hypothalamo-neurohypophysial system (HNS) is the major peptidergic neurosecretory
system through which the brain controls peripheral physiology. The hormones vasopressin …