Migrasomes are migration‐dependent membrane‐bound vesicular structures that contain
cellular contents and small vesicles. Migrasomes grow on the tips or intersections of the …

In the central nervous system, most excitatory post-synapses are small subcellular structures
called dendritic spines. Their structure and morphological remodeling are tightly coupled to …

Branched actin critically contributes to membrane trafficking by regulating membrane
curvature, dynamics, fission, and transport. However, how actin dynamics are controlled at …

How cells tightly control the formation and turnover of branched actin filament arrays to drive
cell motility, endocytosis, and other cellular processes is still not well understood. Here, we …

With increasing age, bone tissue undergoes significant alterations in composition,
architecture, and metabolic functions, probably causing senile osteoporosis. Osteoporosis …

Integrin activation is required for neutrophil functions. Impaired integrin activation on
neutrophils is the hallmark of leukocyte adhesion deficiency (LAD) syndrome in humans …

The Arp2/3 (Actin-related proteins 2/3) complex is activated by WASP (Wiskott–Aldrich
syndrome protein) family proteins to nucleate branched actin filaments that are important for …

Osteoclasts are unique cells that destroy the mineralized matrix of the skeleton. There is a
“love–hate” relationship between the osteoclasts and the bone matrix, whereby the …

Clathrin-mediated endocytosis (CME) is the major route through which cells internalise
various substances and recycle membrane components. Via the coordinated action of many …

Cortactin, a member of the actin-binding protein family, plays an important role in cell
movement involving the cytoskeleton, as cell movement mediated by cortactin may induce …