Cells require actin nucleation factors to catalyze the formation of actin networks and
elongation factors to control the rate and extent of actin polymerization. Earlier models …

Unlike the WASP family of Arp2/3 complex activators, WISH/DIP/SPIN 90 (WDS) family
proteins activate actin filament nucleation by the Arp2/3 complex without the need for a …

Objective—Actin cytoskeleton assembly and organization, as a result of focal adhesion (FA)
formation during cell adhesion, are dependent on reactive oxygen species and the cellular …

The actin cytoskeleton can form many different types of dynamic supramolecular arrays-from
linear bundles to branched actin filament networks which underlie its functional diversity and …

There are reports of fluorochloridone (FLC)-induced male reproductive toxicity, but the
underlying toxicological mechanisms remain unknown. In this study, we looked at how FLC …

The thyroid hormone triiodothyronine (T3) plays a fundamental role in growth regulation,
differentiation, metabolism and cellular movement. These processes are particularly …

Malregulation of the actin cytoskeleton enhances tumor cell motility and invasion. The actin-
binding protein cortactin facilitates branched actin network formation through activation of …

NK cell's killing is a tightly regulated process under the control of specific cytoskeletal
proteins. This includes Wiskott–Aldrich syndrome protein, Wiskott–Aldrich syndrome protein …

Cancer cells exploit different strategies to escape from the primary tumor, gain access to the
circulation, disseminate throughout the body, and form metastases, the leading cause of …

Delivery of bacterial toxins to host cells is hindered by host protective barriers. This
obstruction dictates a remarkable efficiency of toxins, a single copy of which may kill a host …