[HTML][HTML] Antimicrobial peptides for combating drug-resistant bacterial infections

J Xuan, W Feng, J Wang, R Wang, B Zhang, L Bo… - Drug Resistance …, 2023 - Elsevier
The problem of drug resistance due to long-term use of antibiotics has been a concern for
years. As this problem grows worse, infections caused by multiple bacteria are expanding …

[HTML][HTML] Antimicrobial peptides: A new hope in biomedical and pharmaceutical fields

A Moretta, C Scieuzo, AM Petrone, R Salvia… - Frontiers in cellular …, 2021 - frontiersin.org
Antibiotics are essential drugs used to treat pathogenic bacteria, but their prolonged use
contributes to the development and spread of drug-resistant microorganisms. Antibiotic …

Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

Antimicrobial peptides (AMPs): A promising class of antimicrobial compounds

M Erdem Büyükkiraz, Z Kesmen - Journal of Applied …, 2022 - academic.oup.com
Antimicrobial peptides (AMPs) are compounds, which have inhibitory activity against
microorganisms. In the last decades, AMPs have become powerful alternative agents that …

Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications

P Tan, H Fu, X Ma - Nano Today, 2021 - Elsevier
Antibiotic resistance caused by antibiotic abuse, especially the emergence of multi-drug
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …

Antimicrobial ionic liquid‐based materials for biomedical applications

N Nikfarjam, M Ghomi, T Agarwal… - Advanced Functional …, 2021 - Wiley Online Library
Excessive and unwarranted administration of antibiotics has invigorated the evolution of
multidrug‐resistant microbes. There is, therefore, an urgent need for advanced active …

A composite hydrogel with co-delivery of antimicrobial peptides and platelet-rich plasma to enhance healing of infected wounds in diabetes

S Wei, P Xu, Z Yao, X Cui, X Lei, L Li, Y Dong, W Zhu… - Acta biomaterialia, 2021 - Elsevier
Diabetic wound healing remains a major challenge due to its vulnerability to bacterial
infection, as well as the less vascularization and prolonged inflammatory phase. In this …

Strategies employed in the design of antimicrobial peptides with enhanced proteolytic stability

Z Lai, X Yuan, H Chen, Y Zhu, N Dong, A Shan - Biotechnology Advances, 2022 - Elsevier
Due to the alarming developing rate of multidrug-resistant bacterial pathogens, the
development and modification of antimicrobial peptides (AMPs) are unprecedentedly active …

Exploration of bioactive peptides from various origin as promising nutraceutical treasures: In vitro, in silico and in vivo studies

M Manzoor, J Singh, A Gani - Food Chemistry, 2022 - Elsevier
The current health scenarios describe growing public health problems, such as diabetes,
hypertension and cancer. Therefore, researchers focused on studying these health issues …

Generative AI for designing and validating easily synthesizable and structurally novel antibiotics

K Swanson, G Liu, DB Catacutan, A Arnold… - Nature Machine …, 2024 - nature.com
The rise of pan-resistant bacteria is creating an urgent need for structurally novel antibiotics.
Artificial intelligence methods can discover new antibiotics, but existing methods have …