Neutrophil extracellular traps (NETs) are large DNA reticular structures secreted by
neutrophils and decorated with histones and antimicrobial proteins. As a key mechanism for …

Neutrophil infiltration is a hallmark of periodontitis, a prevalent oral inflammatory condition in
which Th17-driven mucosal inflammation leads to destruction of tooth-supporting bone …

Rheumatoid Arthritis (RA) is a common autoimmune disease that targets the synovial joints
leading to arthritis. Although the etiology of RA remains largely unknown, it is clear that …

Neutrophil extracellular traps (NETs) are complex structures released by activated
neutrophils during inflammatory responses. Due to their unique potential for causing tissue …

Innate immune cells play essential roles in modulating both immune defense and
inflammation by expressing a diverse array of cytokines and inflammatory mediators …

Simple Summary Chronic inflammatory arthritis, such as rheumatoid arthritis (RA) and
spondyloarthritis (SpA), often have a significant impact on bone tissue, where bone is not …

Polymorphonuclear neutrophils (PMN) represent one of the first lines of defence against
invading pathogens and are the most abundant leucocytes in the circulation. Generally …

Neutrophils perform essential functions in antimicrobial defense and tissue maintenance at
mucosal barriers. However, a dysregulated neutrophil response and, in particular, the …

Epigenetics is also known as pseudogenetics or postgenetics, and explores heritable
changes in gene expression or cell phenotype through certain mechanisms, without …

Objectives Although elevated levels of neutrophil extracellular traps (NETs) have been
reported in patients with rheumatoid arthritis (RA), the role of NETs in RA and the …