Objective: To describe the pathogenesis of gastrointestinal cytomegalovirus (CMV) disease,
the types and locations of gastrointestinal lesions, the clinical settings in which they occur …

Ganciclovir is a nucleoside analogue of guanosine, a homologue of acyclovir, and the first
antiviral drug to be effective in the treatment of cytomegalovirus (CMV) disease in humans. 1 …

Established for 20 years as the definitive virology reference, the two-volume classic Fields
Virology is in its thoroughly revised, updated Fifth Edition. More than 100 world-renowned …

Protection from cytomegalovirus (CMV) disease in immunocompromised hosts has been
shown to correlate with recovery of the host virus-specific CD8+ T-cell response. The …

Purpose The objective of this review was to summarize the recent literature describing the
current burden of disease due to herpesviruses in the antiviral and transplant era; describe …

Objective: To evaluate the efficacy and safety of ganciclovir for prevention of
cytomegalovirus (CMV) infection and disease. Design: A randomized, placebo-controlled …

Mutations in both the viral phosphotransferase gene, UL97, and the DNA polymerase gene,
UL54, have been shown to confer ganciclovir resistance to cytomegalovirus (CMV) …

Efficient drug delivery to the posterior segment of the eye is a challenging task for the
formulation scientist. Current treatment of chronic back-of-the-eye conditions requires …

Synopsis The DNA polymerase of human herpes viruses, including cytomegalovirus (CMV),
and the reverse transcriptase of human immunodeficiency virus (HIV) are selectively …

Infections of the esophagus are unusual in the general population and strongly imply
immunodeficiency, although immunocompetent individuals are not exempt. HIV infection is …