[HTML][HTML] The impact of the tumor microenvironment on macrophage polarization in cancer metastatic progression

H Wang, MMH Yung, HYS Ngan, KKL Chan… - International journal of …, 2021 - mdpi.com
Rather than primary solid tumors, metastasis is one of the hallmarks of most cancer deaths.
Metastasis is a multistage event in which cancer cells escape from the primary tumor survive …

[HTML][HTML] Breakthrough of extracellular vesicles in pathogenesis, diagnosis and treatment of osteoarthritis

Z Liu, Y Zhuang, L Fang, C Yuan, X Wang, K Lin - Bioactive Materials, 2023 - Elsevier
Osteoarthritis (OA) is a highly prevalent whole-joint disease that causes disability and pain
and affects a patient's quality of life. However, currently, there is a lack of effective early …

[HTML][HTML] The cross-talk between mesenchymal stem cells and immune cells in tissue repair and regeneration

CR Harrell, V Djonov, V Volarevic - International journal of molecular …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) are self-renewable, rapidly proliferating, multipotent stem
cells which reside in almost all post-natal tissues. MSCs possess potent immunoregulatory …

[HTML][HTML] Regulatory T cells (Tregs) in liver fibrosis

K Wu, Q Qian, J Zhou, D Sun, Y Duan, X Zhu… - Cell death …, 2023 - nature.com
The ability of the human liver to both synthesize extracellular matrix (ECM), as well as
regulate fibrogenesis, are integral functions to maintaining homoeostasis. Chronic liver …

[HTML][HTML] Perinatal derivatives: where do we stand? A roadmap of the human placenta and consensus for tissue and cell nomenclature

AR Silini, R Di Pietro, I Lang-Olip, F Alviano… - … in bioengineering and …, 2020 - frontiersin.org
Progress in the understanding of the biology of perinatal tissues has contributed to the
breakthrough revelation of the therapeutic effects of perinatal derivatives (PnD), namely birth …

Amniotic membrane-mesenchymal stromal cells secreted factors and extracellular vesicle-miRNAs: Anti-inflammatory and regenerative features for musculoskeletal …

E Ragni, A Papait, C Perucca Orfei… - Stem Cells …, 2021 - academic.oup.com
Human amniotic membrane-derived mesenchymal stromal cells (hAMSCs) are easily
obtained in large quantities and free from ethical concerns. Promising therapeutic results for …

The immunomodulatory properties of amniotic cells: the two sides of the coin

M Magatti, E Vertua, A Cargnoni, A Silini… - Cell …, 2018 - journals.sagepub.com
Among the many cell types useful in developing therapeutic treatments, human amniotic
cells from placenta have been proposed as valid candidates. Both human amniotic epithelial …

[HTML][HTML] Mesenchymal stromal cells from fetal and maternal placenta possess key similarities and differences: potential implications for their applications in …

A Papait, E Vertua, M Magatti, S Ceccariglia… - Cells, 2020 - mdpi.com
Placenta-derived mesenchymal stromal cells (MSC) have attracted more attention for their
immune modulatory properties and poor immunogenicity, which makes them suitable for …

[HTML][HTML] Comparison of EV-free fraction, EVs, and total secretome of amniotic mesenchymal stromal cells for their immunomodulatory potential: A translational …

A Papait, E Ragni, A Cargnoni, E Vertua… - Frontiers in …, 2022 - frontiersin.org
Amniotic mesenchymal stromal cells (hAMSCs) have unique immunomodulatory properties
demonstrated in vitro and in vivo in various diseases in which the dysregulated immune …

[HTML][HTML] The potential role of extracellular vesicles in COVID-19 treatment: opportunity and challenge

Y Yan, W Zhou, Y Wang, Q Guo, F Zhao… - Frontiers in Molecular …, 2021 - frontiersin.org
SARS-CoV-2 infection has become an urgent public health concern worldwide, severely
affecting our society and economy due to the long incubation time and high prevalence …