[HTML][HTML] The impact of the tumor microenvironment on macrophage polarization in cancer metastatic progression
Rather than primary solid tumors, metastasis is one of the hallmarks of most cancer deaths.
Metastasis is a multistage event in which cancer cells escape from the primary tumor survive …
Metastasis is a multistage event in which cancer cells escape from the primary tumor survive …
[HTML][HTML] Breakthrough of extracellular vesicles in pathogenesis, diagnosis and treatment of osteoarthritis
Z Liu, Y Zhuang, L Fang, C Yuan, X Wang, K Lin - Bioactive Materials, 2023 - Elsevier
Osteoarthritis (OA) is a highly prevalent whole-joint disease that causes disability and pain
and affects a patient's quality of life. However, currently, there is a lack of effective early …
and affects a patient's quality of life. However, currently, there is a lack of effective early …
[HTML][HTML] The cross-talk between mesenchymal stem cells and immune cells in tissue repair and regeneration
CR Harrell, V Djonov, V Volarevic - International journal of molecular …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) are self-renewable, rapidly proliferating, multipotent stem
cells which reside in almost all post-natal tissues. MSCs possess potent immunoregulatory …
cells which reside in almost all post-natal tissues. MSCs possess potent immunoregulatory …
[HTML][HTML] Regulatory T cells (Tregs) in liver fibrosis
K Wu, Q Qian, J Zhou, D Sun, Y Duan, X Zhu… - Cell death …, 2023 - nature.com
The ability of the human liver to both synthesize extracellular matrix (ECM), as well as
regulate fibrogenesis, are integral functions to maintaining homoeostasis. Chronic liver …
regulate fibrogenesis, are integral functions to maintaining homoeostasis. Chronic liver …
[HTML][HTML] Perinatal derivatives: where do we stand? A roadmap of the human placenta and consensus for tissue and cell nomenclature
Progress in the understanding of the biology of perinatal tissues has contributed to the
breakthrough revelation of the therapeutic effects of perinatal derivatives (PnD), namely birth …
breakthrough revelation of the therapeutic effects of perinatal derivatives (PnD), namely birth …
Amniotic membrane-mesenchymal stromal cells secreted factors and extracellular vesicle-miRNAs: Anti-inflammatory and regenerative features for musculoskeletal …
E Ragni, A Papait, C Perucca Orfei… - Stem Cells …, 2021 - academic.oup.com
Human amniotic membrane-derived mesenchymal stromal cells (hAMSCs) are easily
obtained in large quantities and free from ethical concerns. Promising therapeutic results for …
obtained in large quantities and free from ethical concerns. Promising therapeutic results for …
The immunomodulatory properties of amniotic cells: the two sides of the coin
Among the many cell types useful in developing therapeutic treatments, human amniotic
cells from placenta have been proposed as valid candidates. Both human amniotic epithelial …
cells from placenta have been proposed as valid candidates. Both human amniotic epithelial …
[HTML][HTML] Mesenchymal stromal cells from fetal and maternal placenta possess key similarities and differences: potential implications for their applications in …
A Papait, E Vertua, M Magatti, S Ceccariglia… - Cells, 2020 - mdpi.com
Placenta-derived mesenchymal stromal cells (MSC) have attracted more attention for their
immune modulatory properties and poor immunogenicity, which makes them suitable for …
immune modulatory properties and poor immunogenicity, which makes them suitable for …
[HTML][HTML] Comparison of EV-free fraction, EVs, and total secretome of amniotic mesenchymal stromal cells for their immunomodulatory potential: A translational …
A Papait, E Ragni, A Cargnoni, E Vertua… - Frontiers in …, 2022 - frontiersin.org
Amniotic mesenchymal stromal cells (hAMSCs) have unique immunomodulatory properties
demonstrated in vitro and in vivo in various diseases in which the dysregulated immune …
demonstrated in vitro and in vivo in various diseases in which the dysregulated immune …
[HTML][HTML] The potential role of extracellular vesicles in COVID-19 treatment: opportunity and challenge
Y Yan, W Zhou, Y Wang, Q Guo, F Zhao… - Frontiers in Molecular …, 2021 - frontiersin.org
SARS-CoV-2 infection has become an urgent public health concern worldwide, severely
affecting our society and economy due to the long incubation time and high prevalence …
affecting our society and economy due to the long incubation time and high prevalence …