[HTML][HTML] Treatment of congenital coagulopathies, from biologic to biotechnological drugs: The relevance of gene editing (CRISPR/Cas)

JA De Pablo-Moreno, A Miguel-Batuecas… - Thrombosis …, 2023 - Elsevier
Congenital coagulopathies have, throughout the history of medicine, been a focus of
scientific study and of great interest as they constitute an alteration of one of the most …

Noncoding RNAs in Hepatocellular Carcinoma: Potential Applications in Combined Therapeutic Strategies and Promising Candidates of Treatment Response

C Vianello, E Monti, I Leoni, G Galvani, C Giovannini… - Cancers, 2024 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is a leading cause of cancer-related
morbidity and mortality. In the last decade, a breakthrough in the treatment landscape of …

[HTML][HTML] Umbilical cord mesenchymal stem cells overexpressing CXCR7 facilitate treatment of ARDS-associated pulmonary fibrosis via inhibition of Notch/Jag1 …

K Xiao, C Liu, H Wang, F Hou, Y Shi, ZR Qian… - Biomedicine & …, 2023 - Elsevier
The therapeutic efficacy of umbilical cord mesenchymal stem cells (UCMSCs) in acute
respiratory distress syndrome (ARDS) is mainly limited by the efficiency of homing of …

Molecular insights to therapeutic in cancer: role of exosomes in tumor microenvironment, metastatic progression and drug resistance

SS Panda, RK Sahoo, SK Patra, S Biswal… - Drug Discovery …, 2024 - Elsevier
Highlights•Exosomes are involved in tumor microenvironment remodeling.•Tumor cell
heterogeneity and metabolic reprogramming are mediated by exosomes.•Exosomes aid in …

[HTML][HTML] Tumor-derived extracellular vesicles regulate macrophage polarization: role and therapeutic perspectives

L Wang, W Wang, D Hu, Y Liang, Z Liu… - Frontiers in …, 2024 - frontiersin.org
Extracellular vesicles (EVs) are important cell-to-cell communication mediators. This paper
focuses on the regulatory role of tumor-derived EVs on macrophages. It aims to investigate …

[引用][C] Extracellular vesicles in oral oncology: interplay between the tumor microenvironment and disease progression

R Thiruvengadam… - Journal of stomatology …, 2024 - pubmed.ncbi.nlm.nih.gov
Extracellular vesicles in oral oncology: interplay between the tumor microenvironment and
disease progression Extracellular vesicles in oral oncology: interplay between the tumor …