Multiple sclerosis epidemiological trends in Italy highlight the environmental risk factors

M Puthenparampil, P Perini, R Bergamaschi… - Journal of …, 2022 - Springer
Italy is definitely a high-risk country for multiple sclerosis (MS). Over the last 50 years,
several epidemiological studies, including longitudinal surveys, have disclosed that MS …

Incidence of MS has increased markedly over six decades in Denmark particularly with late onset and in women

N Koch-Henriksen, LC Thygesen, E Stenager… - Neurology, 2018 - AAN Enterprises
Objective To describe the pattern of development of incidence of multiple sclerosis (MS)
over 60 years in Denmark with age-period-cohort analyses and seasonality of birth. Methods …

Efficacy and side effects of natalizumab therapy in patients with multiple sclerosis

R Hoepner, S Faissner, A Salmen… - Journal of central …, 2014 - journals.sagepub.com
Natalizumab (Nat) is a humanized monoclonal antibody used for the treatment of relapsing
multiple sclerosis (MS). Nat inhibits lymphocyte migration via the blood brain barrier (BBB) …

Estimated prevalence of multiple sclerosis in Italy in 2015

MA Battaglia, D Bezzini - Neurological sciences, 2017 - Springer
Italy is a high risk area for multiple sclerosis (MS) as confirmed by the numerous prevalence
and incidence studies conducted in several regions/districts of the country. Nevertheless …

Multiple sclerosis epidemiology in Europe

D Bezzini, MA Battaglia - Multiple Sclerosis: Bench to Bedside: Global …, 2017 - Springer
Multiple sclerosis is characterized by a non-homogeneous distribution around the world.
Some authors in past described a latitude gradient, with increasing risk from the equator to …

PM2. 5 levels strongly associate with multiple sclerosis prevalence in the Province of Padua, Veneto Region, North-East Italy

F Tateo, F Grassivaro, M Ermani… - Multiple Sclerosis …, 2019 - journals.sagepub.com
Background: Incidence and prevalence trends of multiple sclerosis (MS) in the Province of
Padua, North-East Italy, suggest that environmental factors may be associated with …

Prevalence of multiple sclerosis in the Lazio region, Italy: use of an algorithm based on health information systems

AM Bargagli, P Colais, N Agabiti, F Mayer, F Buttari… - Journal of …, 2016 - Springer
Compared with other areas of the country, very limited data are available on multiple
sclerosis (MS) prevalence in Central Italy. We aimed to estimate MS prevalence in the Lazio …

Age‐dependent variation of female preponderance across different phenotypes of multiple sclerosis: A retrospective cross‐sectional study

A Miclea, A Salmen, G Zoehner, L Diem… - CNS neuroscience & …, 2019 - Wiley Online Library
Introduction Multiple sclerosis (MS) is an autoimmune disease of the CNS, which
predominantly affects women. Studies investigating the sex distribution in MS are sparse …

Infodemiology and infoveillance of multiple sclerosis in Italy

NL Bragazzi - Multiple sclerosis international, 2013 - Wiley Online Library
Multiple Sclerosis (MS) is a chronic debilitating disease of probable autoimmune
inflammatory nature, whose aetiology is not fully understood, despite the many efforts and …

Prevalence of multiple sclerosis in Tuscany (Central Italy): a study based on validated administrative data

D Bezzini, L Policardo, G Meucci, M Ulivelli… - …, 2016 - karger.com
Background: Multiple Sclerosis (MS) epidemiology in Italy is mainly based on population-
based prevalence studies. Administrative data are an additional source of information, when …