The potential use of natural and structural analogues of antimicrobial peptides in the fight against neglected tropical diseases
Recently, research into the development of new antimicrobial agents has been driven by the
increase in resistance to traditional antibiotics and Emerging Infectious Diseases …
increase in resistance to traditional antibiotics and Emerging Infectious Diseases …
In vivo efficacy and bioavailability of lumefantrine: Evaluating the application of Pheroid technology
LH Du Plessis, K Govender, P Denti… - European Journal of …, 2015 - Elsevier
The oral absorption of compounds with low aqueous solubility, such as lumefantrine, is
typically limited by the dissolution rate in the gastro-intestinal tract, resulting in erratic …
typically limited by the dissolution rate in the gastro-intestinal tract, resulting in erratic …
Improved efficacy of doxycycline in liposomes against Plasmodium falciparum in culture and Plasmodium berghei infection in mice
V Rajendran, C Singh, PC Ghosh - Canadian Journal of …, 2018 - cdnsciencepub.com
The rate at which Plasmodium falciparum is developing resistance to clinically used
antimalarial drugs is alarming. Therefore, there is a compelling need to develop an efficient …
antimalarial drugs is alarming. Therefore, there is a compelling need to develop an efficient …
Assessment of the Induction of Dormant Ring Stages in Plasmodium falciparum Parasites by Artemisone and Artemisone Entrapped in Pheroid Vesicles In Vitro
L Grobler, M Chavchich, RK Haynes… - Antimicrobial Agents …, 2014 - Am Soc Microbiol
The in vitro antimalarial activities of artemisone and artemisone entrapped in Pheroid
vesicles were compared, as was their ability to induce dormancy in Plasmodium falciparum …
vesicles were compared, as was their ability to induce dormancy in Plasmodium falciparum …
Lipid-based Fe-and Zn-nanoformulation is more effective in alleviating Fe-and Zn-deficiency in maize
ZP Stewart, ET Paparozzi, M Djanaguiraman… - Journal of Plant …, 2019 - Taylor & Francis
Improving uptake, translocation, and utilization of foliar applied Fe and Zn is essential for
increasing biomass and grain yield under deficient conditions. We compared the effect of …
increasing biomass and grain yield under deficient conditions. We compared the effect of …
Formulation and evaluation of Pheroid vesicles containing mefloquine for the treatment of malaria
LH Du Plessis, C Helena… - Journal of Pharmacy …, 2014 - academic.oup.com
Objectives Mefloquine (MQ) is an antimalarial drug with high efficacy, often used in the
treatment and chemoprophylaxis of malaria. However, it has low solubility in water, a long …
treatment and chemoprophylaxis of malaria. However, it has low solubility in water, a long …
[HTML][HTML] A toxicity profile of the Pheroid® technology in rodents
J Kleynhans, D Elgar, T Ebenhan, JR Zeevaart… - Toxicology Reports, 2019 - Elsevier
The Pheroid® drug delivery system is now on the threshold of progressing into human
clinical trials for various patented pharmaceutical applications and a systematic investigation …
clinical trials for various patented pharmaceutical applications and a systematic investigation …
In vitro evaluation of the cytotoxic, antibacterial and antioxidant properties of selected chitosan derivatives and melittin
G Jacobs - 2015 - repository.nwu.ac.za
New excipients to improve the oral absorption of drugs are developing significantly.
Polymers are used to enhance drug absorption through the gastrointestinal tract. Chitosan is …
Polymers are used to enhance drug absorption through the gastrointestinal tract. Chitosan is …
[PDF][PDF] Dissolution of engineered iron and calcium nanocompounds and their potential for biofortification of staple crops
JTN Knijnenburg - 2015 - research-collection.ethz.ch
Background Anemia and osteoporosis are global health problems that are mainly caused by
low dietary intakes of iron and calcium. Current strategies to enhance iron and calcium …
low dietary intakes of iron and calcium. Current strategies to enhance iron and calcium …