Cytokines in inflammatory disease
This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines.
Numerous studies have implicated that inflammatory cytokines exert important effects with …
Numerous studies have implicated that inflammatory cytokines exert important effects with …
Autoinflammation and autoimmunity across rheumatic and musculoskeletal diseases
Z Szekanecz, IB McInnes, G Schett… - Nature Reviews …, 2021 - nature.com
Most rheumatic and musculoskeletal diseases (RMDs) can be placed along a spectrum of
disorders, with autoinflammatory diseases (including monogenic systemic autoinflammatory …
disorders, with autoinflammatory diseases (including monogenic systemic autoinflammatory …
Pharmacological inhibitors of the NLRP3 inflammasome
Inflammasomes play a crucial role in innate immunity by serving as signaling platforms
which deal with a plethora of pathogenic products and cellular products associated with …
which deal with a plethora of pathogenic products and cellular products associated with …
Overview of the IL‐1 family in innate inflammation and acquired immunity
CA Dinarello - Immunological reviews, 2018 - Wiley Online Library
Summary The interleukin‐1 (IL‐1) family of cytokines and receptors is unique in immunology
because the IL‐1 family and Toll‐like receptor (TLR) families share similar functions. More …
because the IL‐1 family and Toll‐like receptor (TLR) families share similar functions. More …
Immune crosstalk in cancer progression and metastatic spread: a complex conversation
H Garner, KE de Visser - Nature Reviews Immunology, 2020 - nature.com
Metastatic disease is responsible for approximately 90% of cancer deaths. For successful
dissemination and metastasis, cancer cells must evade detection and destruction by the …
dissemination and metastasis, cancer cells must evade detection and destruction by the …
The IL-1 family of cytokines and receptors in rheumatic diseases
CA Dinarello - Nature Reviews Rheumatology, 2019 - nature.com
More than any other cytokine family, the 11 members of the IL-1 family are associated with
innate immune responses, which occur in acute inflammation and chronic inflammatory …
innate immune responses, which occur in acute inflammation and chronic inflammatory …
COVID-19 and the role of cytokines in this disease
A Hasanvand - Inflammopharmacology, 2022 - Springer
Studies have shown that SARS-CoV-2 has the ability to activate and mature proinflammatory
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …
Interleukin-1 beta—a friend or foe in malignancies?
R Bent, L Moll, S Grabbe, M Bros - International journal of molecular …, 2018 - mdpi.com
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune
cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after …
cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after …
Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders
H Jiang, H He, Y Chen, W Huang, J Cheng… - Journal of Experimental …, 2017 - rupress.org
The NLRP3 inflammasome has been implicated in the pathogenesis of a wide variety of
human diseases. A few compounds have been developed to inhibit NLRP3 inflammasome …
human diseases. A few compounds have been developed to inhibit NLRP3 inflammasome …
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
The NOD-like receptor (NLR) family, pyrin domain–containing protein 3 (NLRP3)
inflammasome is a component of the inflammatory process, and its aberrant activation is …
inflammasome is a component of the inflammatory process, and its aberrant activation is …