The secretion profile of mesenchymal stem cells and potential applications in treating human diseases

Y Han, J Yang, J Fang, Y Zhou, E Candi… - … and Targeted Therapy, 2022 - nature.com
Mesenchymal stromal/stem cells (MSCs) possess multi-lineage differentiation and self-
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …

Reciprocal regulation of mesenchymal stem cells and immune responses

Y Wang, J Fang, B Liu, C Shao, Y Shi - Cell stem cell, 2022 - cell.com
Mesenchymal stem/stromal cells (MSCs) exist in almost all tissues and participate in tissue
regeneration and homeostasis. In-vitro-expanded MSCs are employed as therapeutics for …

Immunomodulatory properties of mesenchymal stem cells/dental stem cells and their therapeutic applications

P Li, Q Ou, S Shi, C Shao - Cellular & molecular immunology, 2023 - nature.com
Mesenchymal stem/stromal cells (MSCs) are widely distributed in the body and play
essential roles in tissue regeneration and homeostasis. MSCs can be isolated from …

MSCs and their exosomes: a rapidly evolving approach in the context of cutaneous wounds therapy

F Marofi, KI Alexandrovna, R Margiana… - Stem Cell Research & …, 2021 - Springer
Currently, mesenchymal stem/stromal stem cell (MSC) therapy has become a promising
option for accelerating cutaneous wound healing. In vivo reports have outlined the robust …

Advances in mesenchymal stem/stromal cell-based therapy and their extracellular vesicles for skin wound healing

MJ Saadh, AA Ramírez-Coronel, RS Saini… - Human Cell, 2023 - Springer
Wound healing is a dynamic and complicated process containing overlapping phases.
Presently, definitive therapy is not available, and the investigation into optimal wound care is …

[HTML][HTML] Therapeutic application of cell secretomes in cutaneous wound healing

D Bormann, A Gugerell, HJ Ankersmit… - Journal of Investigative …, 2023 - Elsevier
Although the application of stem cells to chronic wounds emerged as a candidate therapy in
the previous century, the mechanism of action remains unclear. Recent evidence has …

[HTML][HTML] The role of MSC therapy in attenuating the damaging effects of the cytokine storm induced by COVID-19 on the heart and cardiovascular system

GM Ellison-Hughes, L Colley, KA O'Brien… - Frontiers in …, 2020 - frontiersin.org
The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
that causes coronavirus disease 2019 (COVID-19) has led to 47 m infected cases and 1. 2 m …

[HTML][HTML] PCL/gelatin nanofibers incorporated with starfish polydeoxyribonucleotides for potential wound healing applications

TH Kim, SC Kim, WS Park, IW Choi, HW Kim… - Materials & Design, 2023 - Elsevier
Conventional wound dressings have several shortcomings because they are unspecific and
partially effective for wound healing. To enhance the therapeutic efficiency of wound …

Mesenchymal stem/stromal cells primed by inflammatory cytokines alleviate psoriasis-like inflammation via the TSG-6-neutrophil axis

Y Ding, P Gong, J Jiang, C Feng, Y Li, X Su, X Bai… - Cell Death & …, 2022 - nature.com
Psoriasis is currently an incurable skin disorder mainly driven by a chronic inflammatory
response. We found that subcutaneous application of umbilical cord-derived mesenchymal …

Mesenchymal stem cells alleviate systemic sclerosis by inhibiting the recruitment of pathogenic macrophages

P Gong, Y Ding, R Sun, Z Jiang, W Li, X Su… - Cell Death …, 2022 - nature.com
Systemic sclerosis (SSc) is a recalcitrant autoimmune disease for which there is no cure.
Mesenchymal stem cell (MSC)-based treatment has emerged as a promising therapeutic …