RNF213 gene silencing upregulates transforming growth factor β1 expression in bone marrow‑derived mesenchymal stem cells and is involved in the onset of …

C Wang, C Sun, Y Zhao, H Song… - Experimental and …, 2021 - spandidos-publications.com
Moyamoya disease (MMD) is a chronic and progressive cerebrovascular occlusion disease,
the precise etiology of which is poorly understood. Ring finger protein 213 (RNF213) has …

关于间充质干细胞外泌体与创面微环境研究的一些思考

王达利 - 中华烧伤与创面修复杂志, 2023 - zhsszz.xml-journal.net
自研究者们发现间充质干细胞条件培养基, 外泌体具有与间充质干细胞等效的生物学效应时,
间充质干细胞旁分泌效应的代表产物: 间充质干细胞外泌体就成为间充质干细胞“无细胞” …

Mesenchymal stem cells paracrine proteins from three‐dimensional dynamic culture system promoted wound healing in third‐degree burn models

Y Wang, J Wu, J Chen, C Lu, J Liang… - Bioengineering & …, 2023 - Wiley Online Library
Recovery of skin function remains a significant clinical challenge for deep burns owing to the
severe scar formation and poor appendage regeneration, and stem cell therapy has shown …

Xinkeshu tablets promote angiogenesis in zebrafish embryos and human umbilical vein endothelial cells through multiple signaling pathways

Q Liu, H Zhang, Y An, Y Zhang, Q He, K Liu… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Angiogenesis is particularly important in ischemic
cardiovascular diseases such as coronary heart disease (CHD). Xinkeshu tablets (XKS) are …

Single-cell transcriptome analysis reveals the effectiveness of cytokine priming irrespective of heterogeneity in mesenchymal stromal cells

Z Wan, YF Chen, Q Pan, Y Wang, S Yuan, HY Chin… - Cytotherapy, 2023 - Elsevier
Background aims Mesenchymal stromal cells (MSCs) are recognized as a potential cell-
based therapy for regenerative medicine. Short-term inflammatory cytokine pre-stimulation …

Effect of spheroid size on gene expression profiles of a mouse mesenchymal stem cell line in spheroid culture

A Kuroda, A Mineo, S Shoji, G Inoue… - Bio-Medical …, 2023 - content.iospress.com
BACKGROUND: Mesenchymal stem cell (MSC)-based therapies offer potential for bone
repair. MSC spheroid cultures may harbor enhanced therapeutic potential over MSC …

Enhancing viability and angiogenic efficacy of mesenchymal stem cells via HSP90α and HSP27 regulation based on ROS stimulation for wound healing

I Seo, SW Kim, J Hyun, YJ Kim, HS Park… - Bioengineering & …, 2023 - Wiley Online Library
Light‐based therapy has been reported as a potential preconditioning strategy to induce
intracellular reactive oxygen species (ROS) signaling and improve the angiogenic …

Some thoughts on the research of mesenchymal stem cell exosomes and wound microenvironment

DL Wang - Zhonghua Shao Shang za zhi= Zhonghua Shaoshang …, 2023 - europepmc.org
Since researchers have found that the conditioned medium and exosomes of mesenchymal
stem cells (MSCs) had the biological effects equivalent to those of MSCs, MSC exosomes …

Preconditioning mesenchymal stromal cells with flagellin enhances the anti‑inflammatory ability of their secretome against lipopolysaccharide‑induced acute lung …

R Li, Y Li, X Dong - Molecular Medicine Reports, 2020 - spandidos-publications.com
Acute lung injury (ALI) is a complex condition frequently encountered in the clinical setting.
The aim of the present study was to investigate the effect of conditioned media (CM) from …

TNF-α-Inhibition Improves the Biocompatibility of Porous Polyethylene Implants In Vivo

T Hussain, D Gellrich, S Siemer, CA Reichel… - Tissue Engineering and …, 2021 - Springer
Background: To improve the biocompatibility of porous polyethylene (PPE) implants and
expand their application range for reconstructive surgery in poorly vascularized …