Communication between the periphery and the brain is key for maintaining energy
homeostasis. To do so, peripheral signals from the circulation reach the brain via the …

Melanin-concentrating hormone (MCH) is a small cyclic peptide expressed in all mammals,
mainly in the hypothalamus. MCH acts as a robust integrator of several physiological …

Ghrelin, an acylated peptide hormone of 28 amino acids, is an endogenous ligand of the
released growth hormone secretagogue receptor (GHSR). Ghrelin has been isolated from …

Multidirectional interactions between metabolic organs in the periphery and the central
nervous system have evolved concomitantly with multicellular organisms to maintain whole …

Background Nutrition is a prerequisite for health; yet, there is no special nutritional
assessment or guidance for drug and alcohol dependent individuals, despite the fact that …

Ghrelin is a relatively novel multifaceted hormone that has been found to exert a plethora of
physiological effects. In this review, we found/confirmed that ghrelin has effect on all body …

Much effort has been directed at studying the orexigenic actions of administered ghrelin and
the potential effects of the endogenous ghrelin system on food intake, food reward, body …

Obesity and its comorbidities are long-standing, challenging global health problems. Lack of
exercise, overnutrition, and especially the consumption of fat-rich foods are some of the most …

Ghrelin is an octanoylated peptide that acts via its specific receptor, the growth hormone
secretagogue receptor type 1a (GHSR-1a), and regulates a vast variety of physiological …

Food intake is tightly regulated by homeostatic and reward mechanisms and the adequate
function of both is necessary for the proper maintenance of energy balance. Ghrelin impacts …