Generalized pustular psoriasis (GPP) is a rare, chronic, inflammatory skin disorder
characterized by recurrent flares associated with skin erythema, desquamation, and …

Introduction Hidradenitis suppurativa (HS) is an autoinflammatory skin disease with a high
unmet need for effective medical management. Clinically, it is characterized by inflammatory …

Pyoderma gangrenosum is a rare neutrophilic dermatosis that leads to exceedingly painful
ulcerations of the skin. Although the exact pathogenesis is not yet fully understood, various …

The JAK-STAT signaling pathway mediates important cellular processes such as immune
response, carcinogenesis, cell differentiation, division and death. Therefore, drugs that …

Neutrophilic dermatoses are a group of clinically heterogeneous diseases characterized by
infiltration of neutrophils in the affected tissue. Skin symptoms comprise a spectrum of …

Pyoderma gangrenosum (PG) is a rare inflammatory skin disease classified within the
spectrum of neutrophilic dermatoses. The pathophysiology of PG is yet incompletely …

Cutaneous manifestations of hematologic malignancy represent both a clinical challenge for
the treating physician and a pathophysiological model for advancing the knowledge on …

Hidradenitis suppurativa (HS) is an autoinflammatory skin disorder of the terminal hair
follicle, manifesting with painful nodules, abscesses, draining tunnels, and hypertrophic …

Pyoderma gangrenosum (PG), hidradenitis suppurativa (HS), and the associated
autoinflammatory syndromes, including pyogenic arthritis, pyoderma gangrenosum, and …

Introduction This scoping review explores the effectiveness of IL-1 pathway inhibitors in
managing PSTPIP1-associated inflammatory diseases (PAID). These diseases are marked …