Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications

Q Tuo, S Zhang, P Lei - Medicinal research reviews, 2022 - Wiley Online Library
Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …

The inflammatory response in stroke

Q Wang, XN Tang, MA Yenari - Journal of neuroimmunology, 2007 - Elsevier
Recent works in the area of stroke and brain ischemia has demonstrated the significance of
the inflammatory response accompanying necrotic brain injury. Acutely, this response …

标准外伤大骨瓣开颅术在重型颅脑损伤救治中的应用

吕立权, 江基尧 - 国外医学: 神经病学. 神经外科学分册, 2002 - cqvip.com
近年来的临床研究显示标准外伤大骨瓣手术能使重型颅脑损伤病人死亡率显著下降.
标准外伤大骨瓣暴露范围广, 能清除约95% 单侧幕上急性颅内血肿, 彻底清除坏死组织 …

Pathophysiology and therapy of experimental stroke

KA Hossmann - Cellular and molecular neurobiology, 2006 - Springer
1. Stroke is the neurological evidence of a critical reduction of cerebral blood flow in a
circumscribed part of the brain, resulting from the sudden or gradually progressing …

[PDF][PDF] Свободные радикалы и клеточная хемилюминесценция

ЮА Владимиров, ЕВ Проскурина - Успехи биологической химии, 2009 - chemilum.ru
МИтОгЕНЕтИчЕСКИЕ ЛУчИ И СВЕРХСЛАбОЕ СВЕчЕНИЕ Представление о том, что
живые клетки человека и животных могут излучать слабый свет в ультрафиолетовой …

Anti-high mobility group box-1 monoclonal antibody protects the blood–brain barrier from ischemia-induced disruption in rats

J Zhang, HK Takahashi, K Liu, H Wake, R Liu, T Maruo… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—High mobility group box-1 (HMGB1) exhibits inflammatory
cytokine-like activity in the extracellular space. We previously demonstrated that intravenous …

Uric acid protects neurons against excitotoxic and metabolic insults in cell culture, and against focal ischemic brain injury in vivo

ZF Yu, AJ Bruce‐Keller, Y Goodman… - Journal of …, 1998 - Wiley Online Library
Uric acid is a well‐known natural antioxidant present in fluids and tissues throughout the
body. Oxyradical production and cellular calcium overload are believed to contribute to the …

Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults

AJ Bruce‐Keller, G Umberger, R McFall… - Annals of Neurology …, 1999 - Wiley Online Library
Food restriction (FR) in rodents is known to extend life span, reduce the incidence of age‐
related tumors, and suppress oxidative damage to proteins, lipids, and DNA in several organ …

Organophosphate-induced brain damage: mechanisms, neuropsychiatric and neurological consequences, and potential therapeutic strategies

Y Chen - Neurotoxicology, 2012 - Elsevier
Organophosphate (OP)-induced brain damage is defined as progressive damage to the
brain, resulting from the cholinergic neuronal excitotoxicity and dysfunction induced by OP …

Brain tissue oxygen–directed management and outcome in patients with severe traumatic brain injury

AM Spiotta, MF Stiefel, VH Gracias, AM Garuffe… - Journal of …, 2010 - thejns.org
Object The object of this study was to determine whether brain tissue oxygen (PbtO 2)–
based therapy or intracranial pressure (ICP)/cerebral perfusion pressure (CPP)–based …