Objective: Chronic lymphocytic leukemia (CLL) is a disease of nonproliferating and mature-
appearing B lymphocytes. Insulin-like growth factor-1 (IGF-1) is a small peptide hormone …

Acute megakaryoblastic leukemia (AMKL) is a rare type of acute myeloid leukemia that
evolved from primitive megakaryoblasts. We report a case of non-Down syndrome AMKL …

In this issue of Cancer Discovery, Lopez and colleagues show that the aggressive acute
leukemic phenotype caused by the chimeric transcription factor CBFA2T3–GLIS2 varies …

En esta revisión se describen las características generales de las formas más frecuentes de
leucemia, especialmente de la leucemia infantil, que ha sido el modelo de estudio para la …

Pediatric acute myeloid leukemia (AML) is a genetically heterogeneous disease distinct from
the adult with few chromosomal alterations and often driven by a single potent oncogene …

Objective To study the clinical features and prognosis of children with acute megakaryocytic
leukemia (AMKL) and the clinical effect of acute myeloid leukemia 03 (AML03) regimen for …

Acute myeloid leukaemia (AML) is the most common aggressive human leukaemia. It is
frequently characterised by the stepwise acquisition of multiple somatic mutations in stem …

The recent chemotherapeutic approaches to acute myeloid leukemia (AML) management
reached the limits, achieving overall survival rate of approximately 70%. An intensification of …

In the recent years, massively parallel sequencing approaches identified hundreds of
mutated genes in cancer (1) providing an unprecedented amount of information about …