Ubiquitin-proteasome mediated protein turnover is an important regulatory mechanism of
cellular function in eukaryotes. Extensive studies have linked the ubiquitin-proteasome …

In eukaryotic cells, a large number of proteins are modified by ubiquitination, which leads to
proteasomal degradation or change in protein function. The protein ubiquitination process …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes cryptococccosis
in immunocompromised patients as well as immunocompetent individuals. Host cell surface …

The ubiquitin–proteasome system (UPS) regulates protein quality or control and plays
essential roles in several biological and biochemical processes in fungi. Here, we present …

Cryptococcus neoformans (C. neoformans) is an opportunistic fungal pathogen that mainly
infects immunocompromised individuals such as AIDS patients. Although cell surface …

Iron availability is a key determinant of virulence in the pathogenic fungus C ryptococcus
neoformans. Previous work revealed that the ESCRT (endosomal sorting complex required …

Ubiquitination is an essential protein modification in eukaryotic cells, which is reversible.
Deubiquitinating enzymes (DUBs) catalyze deubiquitination process to reverse …

Cryptococcal disease is estimated to affect nearly a quarter of a million people annually.
Environmental isolates of Cryptococcus deneoformans, which make up 15 to 30% of clinical …

Cellular responses to external stress allow microorganisms to adapt to a vast array of
environmental conditions, including infection sites. The molecular mechanisms behind these …

Ubiquitination is a key regulatory mechanism that affects numerous important biological
processes, including cellular differentiation and pathogenesis in eukaryotic cells. Attachment …