Integrative genomic profiling of human prostate cancer
Annotation of prostate cancer genomes provides a foundation for discoveries that can
impact disease understanding and treatment. Concordant assessment of DNA copy number …
impact disease understanding and treatment. Concordant assessment of DNA copy number …
Human mitochondrial pyrroline-5-carboxylate reductase 1 promotes invasiveness and impacts survival in breast cancers
J Ding, ML Kuo, L Su, L Xue, F Luh, H Zhang… - …, 2017 - academic.oup.com
Human mitochondrial pyrroline-5-carboxylate reductase (PYCR) is a house-keeping
enzyme that catalyzes the reduction of Δ1-pyrroline-5-carboxylate to proline. This enzymatic …
enzyme that catalyzes the reduction of Δ1-pyrroline-5-carboxylate to proline. This enzymatic …
LNCaP Atlas: Gene expression associated with in vivoprogression to castration-recurrent prostate cancer
TL Romanuik, G Wang, O Morozova, A Delaney… - BMC medical …, 2010 - Springer
Background There is no cure for castration-recurrent prostate cancer (CRPC) and the
mechanisms underlying this stage of the disease are unknown. Methods We analyzed the …
mechanisms underlying this stage of the disease are unknown. Methods We analyzed the …
The role of mRNA splicing in prostate cancer
Alternative splicing (AS) is a crucial step in gene expression. It is subject to intricate
regulation, and its deregulation in cancer can lead to a wide array of neoplastic phenotypes …
regulation, and its deregulation in cancer can lead to a wide array of neoplastic phenotypes …
[HTML][HTML] Predictive models for newly diagnosed prostate cancer patients
WT Lowrance, PT Scardino - Reviews in urology, 2009 - ncbi.nlm.nih.gov
Accurate risk assessment is of paramount importance to newly diagnosed prostate cancer
patients and their physicians. Risk prediction models help identify those at high (or low) risk …
patients and their physicians. Risk prediction models help identify those at high (or low) risk …
[HTML][HTML] Expression signatures that correlated with Gleason score and relapse in prostate cancer
M Bibikova, E Chudin, A Arsanjani, L Zhou, EW Garcia… - Genomics, 2007 - Elsevier
Predicting prognosis in prostate carcinoma remains a challenge when using clinical and
pathologic criteria only. We used an array-based DASL® assay to identify molecular …
pathologic criteria only. We used an array-based DASL® assay to identify molecular …
Crystal structure of human pyrroline-5-carboxylate reductase
Pyrroline-5-carboxylate reductase (P5CR) is a universal housekeeping enzyme that
catalyzes the reduction of Δ1-pyrroline-5-carboxylate (P5C) to proline using NAD (P) H as …
catalyzes the reduction of Δ1-pyrroline-5-carboxylate (P5C) to proline using NAD (P) H as …
Gene expression relationship between prostate cancer cells of Gleason 3, 4 and normal epithelial cells as revealed by cell type-specific transcriptomes
LE Pascal, RZN Vêncio, LS Page, ES Liebeskind… - BMC cancer, 2009 - Springer
Background Prostate cancer cells in primary tumors have been typed CD10-/CD13-/CD24
hi/CD26+/CD38 lo/CD44-/CD104-. This CD phenotype suggests a lineage relationship …
hi/CD26+/CD38 lo/CD44-/CD104-. This CD phenotype suggests a lineage relationship …
[图书][B] Cancer diagnostics with DNA microarrays
S Knudsen - 2006 - books.google.com
Authored by an international authority in the field, Cancer Diagnostics with DNA Microarrays
is a complete reference work on the rapidly growing use of DNA microarray data in the …
is a complete reference work on the rapidly growing use of DNA microarray data in the …
[HTML][HTML] Deciphering the effects of PYCR1 on cell function and its associated mechanism in hepatocellular carcinoma
Y Xu, W Zuo, X Wang, Q Zhang, X Gan… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Overexpression of pyrroline-5-carboxylate reductase 1 (PYCR1) has been associated with
the development of certain cancers; however, no studies have specifically examined the role …
the development of certain cancers; however, no studies have specifically examined the role …