Uric acid (UA) is the end product of purine nucleotide metabolism in the human body.
Hyperuricemia is an abnormally high level of UA in the blood and may result in arthritis and …

Substantial evidence suggests that chronic hyperuricemia is an independent risk factor for
hypertension, metabolic syndrome, chronic kidney disease (CKD) and cardiovascular …

Despite improvements in pharmacotherapy, morbidity and mortality rates in community-
based populations with chronic heart failure still remain high. The increase in medical …

Aims Blood uric acid (UA) levels are frequently elevated in patients with heart failure and
reduced ejection fraction (HFrEF), may lead to gout and are associated with worse …

Background The sodium-glucose cotransporter-2 inhibitor empagliflozin decreases the risk
of cardiovascular death or hospitalization for heart failure (HF) in patients with HF with …

Objective: To assess the prognostic cut-off values of serum uric acid (SUA) in predicting fatal
and morbid heart failure in a large Italian cohort in the frame of the Working Group on Uric …

Hyperuricemia is a metabolic disease caused by purine nucleotide metabolism disorder.
The prevalence of hyperuricemia is increasing worldwide, with a growing trend in the …

The relation between uric acid (UA) and heart failure has been described; however, there is
little detail concerning acute heart failure (AHF) in patients with reduced versus preserved …

Background The joint association of hyperuricemia and chronic kidney disease (CKD) with
mortality in patients with chronic heart failure (CHF) is not conclusive. Methods This …

Background: Conflicting results have been reported on the prognostic significance of serum
uric acid (SUA) in patients with acute heart failure (AHF). This meta-analysis aimed to …