Bacterial genome sequencing in clinical microbiology: a pathogen-oriented review

F Tagini, G Greub - European journal of clinical microbiology & infectious …, 2017 - Springer
In recent years, whole-genome sequencing (WGS) has been perceived as a technology with
the potential to revolutionise clinical microbiology. Herein, we reviewed the literature on the …

Interpreting whole genome sequencing for investigating tuberculosis transmission: a systematic review

HA Hatherell, C Colijn, HR Stagg, C Jackson… - BMC medicine, 2016 - Springer
Background Whole genome sequencing (WGS) is becoming an important part of
epidemiological investigations of infectious diseases due to greater resolution and cost …

Whole genome sequencing of Mycobacterium tuberculosis for detection of recent transmission and tracing outbreaks: a systematic review

V Nikolayevskyy, K Kranzer, S Niemann, F Drobniewski - Tuberculosis, 2016 - Elsevier
Contact tracing complemented with genotyping is considered an important means of
understanding person-to-person transmission of tuberculosis (TB). It still remains unclear …

Whole genome sequence analysis of a large isoniazid-resistant tuberculosis outbreak in London: a retrospective observational study

N Casali, A Broda, SR Harris, J Parkhill, T Brown… - PLoS …, 2016 - journals.plos.org
Background A large isoniazid-resistant tuberculosis outbreak centred on London, United
Kingdom, has been ongoing since 1995. The aim of this study was to investigate the power …

[HTML][HTML] Role and value of whole genome sequencing in studying tuberculosis transmission

V Nikolayevskyy, S Niemann, R Anthony… - Clinical Microbiology …, 2019 - Elsevier
Background Tuberculosis (TB) remains a serious public health threat worldwide.
Theoretically ultimate resolution of whole genome sequencing (WGS) for Mycobacterium …

Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages

JE Phelan, F Coll, I Bergval, RM Anthony, R Warren… - BMC genomics, 2016 - Springer
Abstract Background Approximately 10% of the Mycobacterium tuberculosis genome is
made up of two families of genes that are poorly characterized due to their high GC content …

[HTML][HTML] Mycobacterium avium in community and household water, suburban Philadelphia, Pennsylvania, USA, 2010–2012

L Lande, DC Alexander, RJ Wallace Jr… - Emerging infectious …, 2019 - ncbi.nlm.nih.gov
Attention to environmental sources of Mycobacterium avium complex (MAC) infection is a
vital component of disease prevention and control. We investigated MAC colonization of …

Whole genome sequencing reveals genomic heterogeneity and antibiotic purification in Mycobacterium tuberculosis isolates

PA Black, M De Vos, GE Louw, RG Van der Merwe… - BMC genomics, 2015 - Springer
Background Whole genome sequencing has revolutionised the interrogation of
mycobacterial genomes. Recent studies have reported conflicting findings on the genomic …

Clinical value of whole-genome sequencing of Mycobacterium tuberculosis

HE Takiff, O Feo - The Lancet Infectious Diseases, 2015 - thelancet.com
Whole-genome sequencing (WGS) is now common as a result of new technologies that can
rapidly sequence a complete bacterial genome for US $500 or less. Many studies have …

Tracing Mycobacterium tuberculosis transmission by whole genome sequencing in a high incidence setting: a retrospective population-based study in East …

K Bjorn-Mortensen, B Soborg, A Koch, K Ladefoged… - Scientific reports, 2016 - nature.com
Abstract In East Greenland, a dramatic increase of tuberculosis (TB) incidence has been
observed in recent years. Classical genotyping suggests a genetically similar …