[HTML][HTML] Pharmacological agents targeting thromboinflammation in COVID-19: review and implications for future research

B Bikdeli, MV Madhavan, A Gupta… - Thrombosis and …, 2020 - thieme-connect.com
Coronavirus disease 2019 (COVID-19), currently a worldwide pandemic, is a viral illness
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The …

Fifty Years of Research in ARDS.The Epidemiology of Acute Respiratory Distress Syndrome. A 50th Birthday Review

T Pham, GD Rubenfeld - American journal of respiratory and critical …, 2017 - atsjournals.org
Since its first description 50 years ago, no other intensive care syndrome has been as
extensively studied as acute respiratory distress syndrome (ARDS). Despite this extensive …

Aspirin use is associated with decreased mechanical ventilation, intensive care unit admission, and in-hospital mortality in hospitalized patients with coronavirus …

JH Chow, AK Khanna, S Kethireddy… - Anesthesia & …, 2021 - journals.lww.com
BACKGROUND: Coronavirus disease-2019 (COVID-19) is associated with
hypercoagulability and increased thrombotic risk in critically ill patients. To our knowledge …

[HTML][HTML] Circulating Von Willebrand factor and high molecular weight multimers as markers of endothelial injury predict COVID-19 in-hospital mortality

A Philippe, R Chocron, N Gendron, O Bory, A Beauvais… - Angiogenesis, 2021 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) is a respiratory disease
associated with endotheliitis and microthrombosis. Objectives To correlate endothelial …

Clinical trials in acute respiratory distress syndrome: challenges and opportunities

MA Matthay, DF McAuley, LB Ware - The Lancet Respiratory …, 2017 - thelancet.com
This year is the 50th anniversary of the first description of acute respiratory distress
syndrome (ARDS). Since then, much has been learned about the pathogenesis of lung …

Immunothrombosis in acute respiratory distress syndrome: cross talks between inflammation and coagulation

F Frantzeskaki, A Armaganidis, SE Orfanos - Respiration, 2017 - karger.com
Acute respiratory distress syndrome (ARDS) is defined as a syndrome of acute onset, with
bilateral opacities on chest imaging and respiratory failure not caused by cardiac failure …

Acute respiratory distress syndrome

M Confalonieri, F Salton… - European Respiratory …, 2017 - Eur Respiratory Soc
Since its first description, the acute respiratory distress syndrome (ARDS) has been
acknowledged to be a major clinical problem in respiratory medicine. From July 2015 to July …

[HTML][HTML] Approaches towards fighting the COVID‑19 pandemic

SC Tsai, CC Lu, DT Bau, YJ Chiu… - International …, 2021 - spandidos-publications.com
Abstract The coronavirus disease 2019 (COVID‑19) outbreak, which has caused> 46
millions confirmed infections and> 1.2 million coronavirus related deaths, is one of the most …

[HTML][HTML] Blood platelets and sepsis pathophysiology: a new therapeutic prospect in critical ill patients?

A Dewitte, S Lepreux, J Villeneuve, C Rigothier… - Annals of intensive …, 2017 - Springer
Beyond haemostasis, platelets have emerged as versatile effectors of the immune response.
The contribution of platelets in inflammation, tissue integrity and defence against infections …

[HTML][HTML] Diagnosis and treatment of acute pulmonary inflammation in critically ill patients: the role of inflammatory biomarkers

S Chalmers, A Khawaja, PM Wieruszewski… - World journal of …, 2019 - ncbi.nlm.nih.gov
Pneumonia and acute respiratory distress syndrome are common and important causes of
respiratory failure in the intensive care unit with a significant impact on morbidity, mortality …