Inflammation is a complex response of the body to exogenous and endogenous insults.
Chronic and systemic diseases are attributed to uncontrolled inflammation. Molecules …

Despite 50 years of extensive research, no definite drug is currently available to treat acute
respiratory distress syndrome (ARDS), and the supportive therapies remain the mainstay of …

Acute lung injury (ALI), a common cause of morbidity and mortality in intensive care units,
results from either direct intra-alveolar injury or indirect injury following systemic …

While the inflammatory response to severe pneumonia is paramount in limiting and
resolving the infection, excessive inflammation can lead to deleterious effects. We theorized …

In vitro circulation (cardiopulmonary bypass, CPB) has been widely used in heart surgery. In
the past, it was believed that the reduction of platelet count and impaired platelet function …

Purpose Air pollutant exposure constitutes a serious risk factor for the emergence or
aggravation of (existing) pulmonary disease. The impact of pre-intensive care ambient air …

Introduction Sepsis is a leading global cause of morbidity and mortality, and is more
common at the extremes of age. Moreover, the cost of in-hospital care for elderly patients …

Objectives: Staphylococcus aureus bloodstream infection is associated with considerable
mortality. Experimental models suggest a direct antistaphylococcal effect of acetylsalicylic …

Background Acute respiratory distress syndrome (ARDS) is a life-threatening condition with
high mortality that imposes a serious medical burden. Antiplatelet therapy is a potential …

Background Severe pneumonia is the predominant cause for acute respiratory distress
syndrome (ARDS). Identification of ARDS from patients with severe pneumonia remains a …