[HTML][HTML] Mapping the lymphatic system across body scales and expertise domains: A report from the 2021 National Heart, Lung, and Blood Institute workshop at the …

D Singhal, K Börner, EL Chaikof, M Detmar… - Frontiers in …, 2023 - frontiersin.org
Enhancing our understanding of lymphatic anatomy from the microscopic to the anatomical
scale is essential to discern how the structure and function of the lymphatic system interacts …

[HTML][HTML] The physiological functions of lymphangiocrine signals

C Liu, J Li - Trends in Endocrinology & Metabolism, 2023 - cell.com
It has been demonstrated that the lymphatic system plays important roles in tissue
development and the progress of diseases. Recent studies identified that lymphatic …

[HTML][HTML] Tenascin-C in tissue repair after myocardial infarction in humans

K Matsui, S Torii, S Hara, K Maruyama, T Arai… - International Journal of …, 2023 - mdpi.com
Adverse ventricular remodeling after myocardial infarction (MI) is progressive ventricular
dilatation associated with heart failure for weeks or months and is currently regarded as the …

[HTML][HTML] Differential regulation of lymphatic junctional morphology and the potential effects on cardiovascular diseases

AM Peluzzo, M Bkhache, LNH Do, MV Autieri… - Frontiers in …, 2023 - frontiersin.org
The lymphatic vasculature provides an essential route to drain fluid, macromolecules, and
immune cells from the interstitium as lymph, returning it to the bloodstream where the …

Intrinsic and extrinsic contributors to the cardiac benefits of exercise

MH Hastings, C Castro, R Freeman… - Basic to Translational …, 2024 - jacc.org
Among its many cardiovascular benefits, exercise training improves heart function and
protects the heart against age-related decline, pathological stress, and injury. Here, we …

[HTML][HTML] The Obesity-Autophagy-Cancer Axis: Mechanistic Insights and Therapeutic Perspectives

AB Behrooz, M Cordani, A Fiore, M Donadelli… - Seminars in Cancer …, 2024 - Elsevier
Autophagy, a self-degradative process vital for cellular homeostasis, plays a significant role
in adipose tissue metabolism and tumorigenesis. This review aims to elucidate the complex …

Role of the Lymphatics in Cardiac Disease

STE Cooper, AB Lokman, PR Riley - … , Thrombosis, and Vascular …, 2024 - Am Heart Assoc
Cardiovascular diseases remain the largest cause of death worldwide with recent evidence
increasingly attributing the development and progression of these diseases to an …

[HTML][HTML] Hydrogen sulfide donor activates AKT-eNOS signaling and promotes lymphatic vessel formation

RV Aithabathula, N Pervaiz, I Kathuria, M Swanson… - Plos one, 2023 - journals.plos.org
The lymphatic network is pivotal for various physiological functions in the human body.
Accumulated evidence supports the role of therapeutic lymphangiogenesis in the treatment …

Mechanisms of Myocardial Edema Development in CVD Pathophysiology

DG Kiseleva, TV Kirichenko, YV Markina… - Biomedicines, 2024 - mdpi.com
Myocardial edema is the excess accumulation of fluid in the myocardial interstitium or
cardiac cells that develops due to changes in capillary permeability, loss of glycocalyx …

Targeting lymphatic function in cardiovascular-kidney-metabolic syndrome: preclinical methods to analyze lymphatic function and therapeutic opportunities

JWM Fowler, LJ Song, K Tam… - Frontiers in …, 2024 - frontiersin.org
The lymphatic vascular system spans nearly every organ in the body and serves as an
important network that maintains fluid, metabolite, and immune cell homeostasis. Recently …