PURPOSE: To revise the staging system for cutaneous melanoma under the auspices of the
American Joint Committee on Cancer (AJCC). MATERIALS AND METHODS: The prognostic …

Melanoma of unknown primary site (MUP) comprises 3–4% of all melanomas. It mostly
presents in lymph nodes (LNs), followed by subcutaneous sites, and visceral organs; …

PURPOSE: The American Joint Committee on Cancer (AJCC) recently proposed major
revisions of the tumor-node-metastases (TNM) categories and stage groupings for …

Abstract Background: CC chemokine receptor-7 (CCR7), which plays a critical role in the
migration of activated dendritic cells to regional lymph nodes via afferent lymphatic vessels …

The chemokine receptors CC chemokine receptor (CCR) 7 and CXC chemokine receptor
(CXCR) 4 have been implicated in cancer metastasis. To evaluate whether CXCR4 is …

PURPOSE To perform a double-blind randomized trial with American Joint Commission on
Cancer (AJCC) stage III melanoma patients for the following reasons:(1) to confirm our …

Chemokines and their receptors play key roles in leukocyte trafficking and are also
implicated in cancer metastasis to specific organs. Here we show that mouse B16F10 …

Written by the leading melanoma experts from the United States, Australia, and Europe, this
new edition incorporates the clinical outcomes of more than 70,000 patients treated at major …

The American Joint Committee on Cancer Melanoma Staging Committee proposes major
changes to the TNM classification and the stage grouping for cutaneous melanoma …

PURPOSE To critically review the accuracy of the current American Joint Committee on
Cancer (AJCC) staging system for cutaneous melanoma and propose a more useful staging …