HIV infection and older Americans: the public health perspective

JT Brooks, K Buchacz, KA Gebo… - American journal of …, 2012 - ajph.aphapublications.org
HIV disease is often perceived as a condition affecting young adults. However,
approximately 11% of new infections occur in adults aged 50 years or older. Among persons …

Sex-based differences in HIV type 1 pathogenesis

MM Addo, M Altfeld - The Journal of infectious diseases, 2014 - academic.oup.com
Human immunodeficiency virus (HIV) remains a global infectious diseases threat that
disproportionally affects women. Beyond social and political factors, biological and genetic …

[HTML][HTML] Estrogen and COVID-19 symptoms: associations in women from the COVID Symptom Study

R Costeira, KA Lee, B Murray, C Christiansen… - PLoS …, 2021 - journals.plos.org
It has been widely observed that adult men of all ages are at higher risk of developing
serious complications from COVID-19 when compared with women. This study aimed to …

[HTML][HTML] Phenotype and susceptibility to HIV infection of CD4+ Th17 cells in the human female reproductive tract

M Rodriguez-Garcia, FD Barr, SG Crist, JV Fahey… - Mucosal …, 2014 - Elsevier
Prevention of sexual acquisition of HIV in women requires a substantial increase in our
knowledge about HIV-target cell availability and regulation in the female reproductive tract …

The immune system in menopause: pros and cons of hormone therapy

M Ghosh, M Rodriguez-Garcia, CR Wira - The Journal of steroid …, 2014 - Elsevier
With aging, a general decline in immune function is observed leading to immune-
senescence. Several of these changes are gender specific affecting postmenopausal …

[HTML][HTML] Unveiling uterine aging: much more to learn

Y Wu, M Li, J Zhang, S Wang - Ageing Research Reviews, 2023 - Elsevier
Uterine aging is an important factor that impacts fertility, reproductive health, and uterus-
related diseases; however, it remains poorly explored. Functionally, these disturbances …

Genitourinary changes with aging

CM Mitchell, LE Waetjen - Obstetrics and Gynecology Clinics, 2018 - obgyn.theclinics.com
The menopause transition is a critical time in aging of the female genitourinary tract.
Circulating estradiol changes from cyclical, higher levels in premenopause to varying levels …

Quality and quantity: mucosal CD4+ T cells and HIV susceptibility

LR McKinnon, R Kaul - Current Opinion in HIV and AIDS, 2012 - journals.lww.com
Quality and quantity: mucosal CD4+ T cells and HIV susceptib... : Current Opinion in HIV and
AIDS Quality and quantity: mucosal CD4+ T cells and HIV susceptibility : Current Opinion in …

Mucosal immunity in the female genital tract, HIV/AIDS

J Reis Machado, MV da Silva… - BioMed research …, 2014 - Wiley Online Library
Mucosal immunity consists of innate and adaptive immune responses which can be
influenced by systemic immunity. Despite having been the subject of intensive studies, it is …

[HTML][HTML] Identification of preferential CD4+ T-cell targets for HIV infection in the cervix

VR Joag, LR McKinnon, J Liu, ST Kidane, MH Yudin… - Mucosal …, 2016 - Elsevier
A better understanding of the cellular targets of HIV infection in the female genital tract may
inform HIV prevention efforts. Proposed correlates of cellular susceptibility include the HIV …