A survey of experimental and computational identification of small proteins

J Beals, H Hu, X Li - Briefings in Bioinformatics, 2024 - academic.oup.com
Small proteins (SPs) are typically characterized as eukaryotic proteins shorter than 100
amino acids and prokaryotic proteins shorter than 50 amino acids. Historically, they were …

Decoding the virtual 2D map of the chloroplast proteomes

TK Mohanta, YK Mohanta, A Al-Harrasi - Biological Procedures Online, 2022 - Springer
Background The chloroplast is a semi-autonomous organelle having its own genome and
corresponding proteome. Although chloroplast genomes have been reported, no reports …

Global analysis of cereal microProteins suggests diverse roles in crop development and environmental adaptation

KK Bhati, V Kruusvee, D Straub… - G3: Genes …, 2020 - academic.oup.com
MicroProteins are a class of small single-domain proteins that post-translationally regulate
larger multidomain proteins from which they evolved or which they relate to. They disrupt the …

Protein length distribution is remarkably consistent across Life

Y Nevers, N Glover, C Dessimoz, O Lecompte - bioRxiv, 2021 - biorxiv.org
In every living species, the function of a protein depends on its organisation of structural
domains, and the length of a protein is a direct reflection of this. Because every species …

[HTML][HTML] The role of small proteins in Burkholderia cenocepacia J2315 biofilm formation, persistence and intracellular growth

H Van Acker, A Crabbé, D Jurėnas, L Ostyn, A Sass… - Biofilm, 2019 - Elsevier
Burkholderia cenocepacia infections are difficult to treat due to resistance, biofilm formation
and persistence. B. cenocepacia strain J2315 has a large multi-replicon genome (8.06 Mb) …

In-silico subtractive proteomic analysis approach for therapeutic targets in MDR Salmonella enterica subsp. enterica serovar Typhi str. CT18

N Rahman, I Muhammad, GE Nayab… - Current Topics in …, 2019 - ingentaconnect.com
Objective: In the present study, an attempt has been made for subtractive proteomic analysis
approach for novel drug targets in Salmonella enterica subsp. enterica serover Typhi str …

PSPI: A deep learning approach for prokaryotic small protein identification

M Weston, H Hu, X Li - Frontiers in Genetics, 2024 - frontiersin.org
Small Proteins (SPs) are pivotal in various cellular functions such as immunity, defense, and
communication. Despite their significance, identifying them is still in its infancy. Existing …

[HTML][HTML] “Protein” no longer means what it used to

G Parisi, N Palopoli, SCE Tosatto, MS Fornasari… - Current Research in …, 2021 - Elsevier
Every biologist knows that the word protein describes a group of macromolecules essential
to sustain life on Earth. As biologists, we are invariably trained under a protein paradigm …

Numaswitch, a biochemical platform for the efficient production of disulfide-rich pepteins

BN Nguyen, F Tieves, FG Neusius, H Götzke… - Frontiers in Drug …, 2023 - frontiersin.org
The application of long-chained peptides (> 30 aa) and relatively short proteins (< 300 aa)
has experienced an increasing interest in recent years. However, a reliable production …

[HTML][HTML] Dual quorum-sensing control of purine biosynthesis drives pathogenic fitness of Enterococcus faecalis

S Zlitni, S Bowden, H Sberro, MDT Torres, JM Vaughan… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Enterococcus faecalis is a resident of the human gut, though upon translocation to the blood
or body tissues, it can be pathogenic. Here we discover and characterize two peptide-based …