Advanced Monte Carlo simulations of emission tomography imaging systems with GATE

D Sarrut, M Bała, M Bardiès, J Bert… - Physics in Medicine …, 2021 - iopscience.iop.org
Built on top of the Geant4 toolkit, GATE is collaboratively developed for more than 15 years
to design Monte Carlo simulations of nuclear-based imaging systems. It is, in particular …

Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging

PJ Gawne, F Man, PJ Blower… - Chemical reviews, 2022 - ACS Publications
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

Positronium imaging with the novel multiphoton PET scanner

P Moskal, K Dulski, N Chug, C Curceanu… - Science …, 2021 - science.org
In vivo assessment of cancer and precise location of altered tissues at initial stages of
molecular disorders are important diagnostic challenges. Positronium is copiously formed in …

Colloquium: Positronium physics and biomedical applications

SD Bass, S Mariazzi, P Moskal, E Stępień - Reviews of Modern Physics, 2023 - APS
Positronium is the simplest bound state, built of an electron and a positron. Studies of
positronium in vacuum and its decays in medium tell us about quantum electrodynamics …

Testing CPT symmetry in ortho-positronium decays with positronium annihilation tomography

P Moskal, A Gajos, M Mohammed, J Chhokar… - Nature …, 2021 - nature.com
Charged lepton system symmetry under combined charge, parity, and time-reversal
transformation (CPT) remains scarcely tested. Despite stringent quantum-electrodynamic …

Simulating NEMA characteristics of the modular total-body J-PET scanner—an economic total-body PET from plastic scintillators

P Moskal, P Kowalski, RY Shopa… - Physics in Medicine …, 2021 - iopscience.iop.org
The purpose of the presented research is estimation of the performance characteristics of
the economic total-body Jagiellonian-PET system (TB-J-PET) constructed from plastic …

Hybrid total-body pet scanners—current status and future perspectives

V Nadig, K Herrmann, FM Mottaghy… - European journal of …, 2022 - Springer
Purpose Since the 1990s, PET has been successfully combined with MR or CT systems. In
the past years, especially PET systems have seen a trend towards an enlarged axial field of …

Long axial field of view PET scanners: a road map to implementation and new possibilities

RHJA Slart, C Tsoumpas, AWJM Glaudemans… - European journal of …, 2021 - Springer
In this contribution, several opportunities and challenges for long axial field of view (LAFOV)
PET are described. It is an anthology in which the main issues have been highlighted. A …

[HTML][HTML] Limitations and Pitfalls of FDG-PET/CT in Infection and Inflammation

JP Pijl, PH Nienhuis, TC Kwee… - Seminars in Nuclear …, 2021 - Elsevier
White blood cells activated by either a pathogen or as part of a systemic inflammatory
disease are characterized by high energy consumption and are therefore taking up the …

The OpenGATE ecosystem for Monte Carlo simulation in medical physics

D Sarrut, T Baudier, D Borys, A Etxebeste… - Physics in Medicine …, 2022 - iopscience.iop.org
This paper reviews the ecosystem of GATE, an open-source Monte Carlo toolkit for medical
physics. Based on the shoulders of Geant4, the principal modules (geometry, physics …