Carlos Chagas discovered American trypanosomiasis, also named Chagas disease (CD) in
his honor, just over a century ago. He described the clinical aspects of the disease …

Chagas disease, or American trypanosomiasis, is the result of infection by the parasite
Trypanosoma cruzi. It is endemic in Latin America, and spreading around the globe due to …

The Global Burden of Disease Study (GBD) is a landmark initiative that systematically
quantifies the prevalence, morbidity, and mortality for hundreds of diseases, injuries, and …

Background Chagas disease (CD) is a major public health concern in Latin America and a
potentially serious emerging threat in non-endemic countries. Although the association …

Introduction: Chagas disease, caused by the parasite Trypanosoma cruzi, is a global public
health issue. Current treatments targeting the parasite are limited to two old nitroheterocyclic …

Introduction: Chagas disease (CD) is caused by Trypanosoma cruzi. When acquired, the
disease develops in stages. For diagnosis, laboratory confirmation is required, and an …

Aims This study aimed to estimate the annual mortality risk and its determinants in chronic
Chagas cardiomyopathy. Methods and results We conducted a systematic search in …

Introduction American trypanosomiasis, better known as Chagas disease, is a global public
health issue. Current treatments targeting the causative parasite, Trypanosoma cruzi, are …

Chagas disease is a major neglected tropical disease, transmitted predominantly by
triatomine insect vectors, but also through congenital and oral routes. While endemic in the …

Limited access to Chagas disease diagnosis and treatment is a major obstacle to reaching
the 2020 World Health Organization milestones of delivering care to all infected and ill …