Dilated cardiomyopathy is defined by the presence of left ventricular dilatation and
contractile dysfunction. Genetic mutations involving genes that encode cytoskeletal …

Half of patients with heart failure (HF) have a preserved left ventricular ejection fraction
(HFpEF). Morbidity and mortality in HFpEF are similar to values observed in patients with HF …

Background Systemic effects of COPD are incompletely reflected by established prognostic
assessments. We determined the prognostic value of objectively measured physical activity …

It is important that the medical profession play a significant role in critically evaluating the
use of diagnostic procedures and therapies as they are introduced and tested in the …

Context Heart failure incidence increases with advancing age, and approximately half of
patients with heart failure have preserved left ventricular ejection fraction. Although diastolic …

Context Approximately half of patients with overt congestive heart failure (CHF) have
diastolic dysfunction without reduced ejection fraction (EF). Yet, the prevalence of diastolic …

Heart failure (HF) is a major and growing public health problem in the United States.
Approximately 5 million patients in this country have HF, and over 550 000 patients are …

Background—Noninvasive assessment of diastolic filling by Doppler echocardiography
provides important information about left ventricular (LV) status in selected subsets of …

Objectives: The study sought to evaluate the effects of endurance exercise training (ET) on
endothelial-dependent flow-mediated arterial dilation (FMD) and carotid artery stiffness, and …

Pre-clinical diastolic dysfunction (PDD) has been broadly defined as left ventricular diastolic
dysfunction without the diagnosis of congestive heart failure (HF) and with normal systolic …