Understanding the complex evolution of rapidly mutating viruses with deep sequencing: Beyond the analysis of viral diversity
With the advent of affordable deep sequencing technologies, detection of low frequency
variants within genetically diverse viral populations can now be achieved with …
variants within genetically diverse viral populations can now be achieved with …
Next-generation sequencing analysis of a cluster of hepatitis C virus infections in a haematology and oncology center
K Caraballo Cortes, M Rosińska, M Janiak, M Stępień… - Plos one, 2018 - journals.plos.org
Molecular characterization of early hepatitis C virus (HCV) infection remains rare. Ten out of
78 patients of a hematology/oncology center were found to be HCV RNA positive two to four …
78 patients of a hematology/oncology center were found to be HCV RNA positive two to four …
High confidence identification of intra-host single nucleotide variants for person-to-person influenza transmission tracking in congregate settings
Influenza within-host viral populations are the source of all global influenza diversity and
play an important role in driving the evolution and escape of the influenza virus from human …
play an important role in driving the evolution and escape of the influenza virus from human …
[PDF][PDF] Bioinformatics and statistical methods to study the evolution of primary HCV infection
P Leung - 2018 - unsworks.unsw.edu.au
HCV is a rapidly mutating RNA virus, which affects 170 million people globally. The genome
mutates rapidly to generate many variants (quasispecies) in every infected individual. Yet …
mutates rapidly to generate many variants (quasispecies) in every infected individual. Yet …
Evidence of bottleneck effect on hepatitis C virus transmission between a couple under interferon based therapy
RA da Silva, IMVG de Carvalho, RPA de Matos… - Infection, Genetics and …, 2017 - Elsevier
Issues on the correlation of viral genetic diversity and treatment response to the hepatitis C
infection remain uncertain. The bottleneck effect dictates the characteristics of the viral …
infection remain uncertain. The bottleneck effect dictates the characteristics of the viral …
Ultra-deep sequencing assessment of genetic variability in hepatitis c virus infecting Romanian patients.
ABSTRACT Introduction: Hepatitis C virus (HCV) infection is one of the leading causes of
hepatic disease worldwide. HCV quasispecies are the substrate for selective pressure …
hepatic disease worldwide. HCV quasispecies are the substrate for selective pressure …