Prevalence of exposure of heavy metals and their impact on health consequences

K Rehman, F Fatima, I Waheed… - Journal of cellular …, 2018 - Wiley Online Library
Even in the current era of growing technology, the concentration of heavy metals present in
drinking water is still not within the recommended limits as set by the regulatory authorities in …

[HTML][HTML] The endothelium and its role in regulating vascular tone

A Sandoo, JJCSV van Zanten, GS Metsios… - The open …, 2010 - ncbi.nlm.nih.gov
The endothelium forms an important part of the vasculature and is involved in promoting an
atheroprotective environment via the complementary actions of endothelial cell-derived …

Essential hypertension

FH Messerli, B Williams, E Ritz - The Lancet, 2007 - thelancet.com
Essential hypertension can be defined as a rise in blood pressure of unknown cause that
increases risk for cerebral, cardiac, and renal events. In industrialised countries, the risk of …

Endothelial signaling during development

O Cleaver, DA Melton - Nature medicine, 2003 - nature.com
Blood vessels perfuse all tissues in the body and mediate vital metabolic exchange between
tissues and blood. Increasing evidence, however, points to a direct role for paracrine …

The pathogenesis of pulmonary hypertension in haemodialysis patients via arterio-venous access

F Nakhoul, M Yigla, R Gilman… - Nephrology Dialysis …, 2005 - academic.oup.com
Background. We recently have shown a high incidence of unexplained pulmonary
hypertension (PHT) in end-stage renal disease (ESRD) patients on chronic haemodialysis …

Effects of short‐term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: a randomized, placebo …

J De Jager, A Kooy, PH Lehert, D Bets… - Journal of internal …, 2005 - Wiley Online Library
Objectives. The UK Prospective Diabetes Study (UKPDS) showed that treatment with
metformin decreases macrovascular morbidity and mortality independent of glycaemic …

Long‐term effects of metformin on endothelial function in type 2 diabetes: a randomized controlled trial

J De Jager, A Kooy, C Schalkwijk… - Journal of internal …, 2014 - Wiley Online Library
Objectives We investigated whether metformin can improve endothelial function and
decrease inflammatory activity, and thereby decrease the risk of atherothrombotic disease …

Endothelial dysfunction and low-grade inflammation explain much of the excess cardiovascular mortality in individuals with type 2 diabetes: the Hoorn Study

J de Jager, JM Dekker, A Kooy… - … , and vascular biology, 2006 - Am Heart Assoc
Objective—The mechanisms responsible for the increased cardiovascular disease risk that
accompanies type 2 diabetes (T2D) remain poorly understood. It is commonly held that …

Clinical implications of thermal therapy in lifestyle-related diseases

S Biro, A Masuda, T Kihara… - Experimental Biology and …, 2003 - journals.sagepub.com
Systemic thermal therapy, such as taking a warm-water bath and sauna, induces systemic
vasodilation. It was found that repeated sauna therapy (60° C for 15 min) improved …

Statins and mortality among elderly patients hospitalized with heart failure

JAM Foody, R Shah, D Galusha, FA Masoudi… - Circulation, 2006 - Am Heart Assoc
Background—Small studies suggest that statins may improve mortality in patients with heart
failure (HF). Whether these results are generalizable to a broader group of patients with HF …