Co-delivery of sorafenib and siVEGF based on mesoporous silica nanoparticles for ASGPR mediated targeted HCC therapy

G Zheng, R Zhao, A Xu, Z Shen, X Chen… - European Journal of …, 2018 - Elsevier
Combination with chemotherapeutic drug and gene therapy has been proven highly
effective in suppressing tumor progression. Hence, an asialoglycoprotein receptor (ASGPR) …

Chitosan nanomedicine in cancer therapy: targeted delivery and cellular uptake

A Mushtaq, L Li, L Grøndahl - Macromolecular Bioscience, 2021 - Wiley Online Library
Nanomedicine has gained much attention for the management and treatment of cancers due
to the distinctive physicochemical properties of the drug‐loaded particles. Chitosan's …

[HTML][HTML] Nanotechnology: A revolutionary approach to prevent breast cancer recurrence

AT Alshareeda, MZN Khatijah, BS Al-Sowayan - Asian Journal of Surgery, 2023 - Elsevier
Breast cancer is the most prevalent malignancy in women worldwide and one of the
deadliest after lung cancer. Currently, standard treatment approaches for breast cancers are …

Recent advances in engineered nanoparticles for RNAi-mediated crop protection against insect pests

CE Pugsley, RE Isaac, NJ Warren, OJ Cayre - Frontiers in Agronomy, 2021 - frontiersin.org
Since the discovery of RNA interference (RNAi) in the nematode worm Caenorhabditis
elegans in 1998 by Fire and Mello et al., strides have been made in exploiting RNAi for …

Microbial polysaccharides: An emerging family of natural biomaterials for cancer therapy and diagnostics

VK Sharma, X Liu, DA Oyarzún… - Seminars in Cancer …, 2022 - Elsevier
Microbial polysaccharides (MPs) offer immense diversity in structural and functional
properties. They are extensively used in advance biomedical science owing to their superior …

Formulation and in vitro evaluation of a siRNA delivery nanosystem decorated with gH625 peptide for triple negative breast cancer theranosis

SB Djemaa, S David, K Hervé-Aubert, A Falanga… - European Journal of …, 2018 - Elsevier
The development of an efficient small interfering RNA (siRNA) delivery system has held
scientists interest since the discovery of the RNA interference mechanism (RNAi). This …

Exploring modified chitosan-based gene delivery technologies for therapeutic advancements

AD Gholap, HS Kapare, S Pagar, P Kamandar… - International Journal of …, 2024 - Elsevier
One of the critical steps in gene therapy is the successful delivery of the genes.
Immunogenicity and toxicity are major issues for viral gene delivery systems. Thus, non-viral …

Applications Of Chitosan Based Bionanocomposites In Drug-Delivery And Anticancer Treatment-A Review

M Ali, S Mir, AW Ajlouni, SG Alvi, S Bibi - European Polymer Journal, 2023 - Elsevier
Chitosan is an excellent biopolymer, widely used in drug delivery. Chitosan is a bio-
compatible and biodegradable polysaccharide that is derived from chitin. It can be used in …

Recent advances of polycationic siRNA vectors for cancer therapy

R Bholakant, H Qian, J Zhang, X Huang… - …, 2020 - ACS Publications
Small interfering RNAs (siRNAs) have recently emerged as a new class of
biopharmaceuticals for the treatment of various diseases, including genetic diseases, viral …

Cancer chemoprevention using nanotechnology-based approaches

P Desai, NJ Thumma, PR Wagh, S Zhan… - Frontiers in …, 2020 - frontiersin.org
Cancer research in pursuit of better diagnostic and treatment modalities has seen great
advances in recent years. However, the incidence rate of cancer is still very high. Almost …