Quinoline and quinolone dimers and their biological activities: An overview
XM Chu, C Wang, W Liu, LL Liang, KK Gong… - European journal of …, 2019 - Elsevier
Quinoline and quinolone motifs which act as structural subunits of more complex natural
products are ubiquitous in nature, and they are useful pharmacophores which play a pivotal …
products are ubiquitous in nature, and they are useful pharmacophores which play a pivotal …
Quinolone hybrids and their anti-cancer activities: An overview
F Gao, X Zhang, T Wang, J Xiao - European journal of medicinal chemistry, 2019 - Elsevier
The global pandemic of drug-sensitive cancers and the increasing threat from drug-resistant
cancers make an urgent need to develop more effective anti-cancer candidates. Quinolone …
cancers make an urgent need to develop more effective anti-cancer candidates. Quinolone …
Geminal diheteroatomic motifs: some applications of acetals, ketals, and their sulfur and nitrogen homologues in medicinal chemistry and drug design
YJ Wu, NA Meanwell - Journal of Medicinal Chemistry, 2021 - ACS Publications
Acetals and ketals and their nitrogen and sulfur homologues are often considered to be
unconventional and potentially problematic scaffolding elements or pharmacophores for the …
unconventional and potentially problematic scaffolding elements or pharmacophores for the …
Comprehensive review on various strategies for antimalarial drug discovery
M Mishra, VK Mishra, V Kashaw, AK Iyer… - European journal of …, 2017 - Elsevier
The resistance of malaria parasites to existing drugs carries on growing and progressively
limiting our ability to manage this severe disease and finally lead to a massive global health …
limiting our ability to manage this severe disease and finally lead to a massive global health …
Design and synthesis of harmiquins, harmine and chloroquine hybrids as potent antiplasmodial agents
Malaria remains one of the major health problems worldwide. The lack of an effective
vaccine and the increasing resistance of Plasmodium to the approved antimalarial drugs …
vaccine and the increasing resistance of Plasmodium to the approved antimalarial drugs …
Design, synthesis, herbicidal activity and CoMFA of aryl-formyl piperidinone HPPD inhibitors
Y Fu, M Wang, LX Zhao, SQ Zhang, YX Liu… - Pesticide Biochemistry …, 2021 - Elsevier
Isoxazole, nicotinic acid and benzoic acid are important components in many natural
products and useful synthons to build macrostructures having valuable biological activities …
products and useful synthons to build macrostructures having valuable biological activities …
New structural classes of antimalarials
Malaria remains a major vector borne disease claiming millions of lives worldwide due to
infections caused by Plasmodium sp. Discovery and development of antimalarial drugs have …
infections caused by Plasmodium sp. Discovery and development of antimalarial drugs have …
[图书][B] Studies in natural products chemistry
A Rahman - 2023 - books.google.com
Studies in Natural Products Chemistry, Volume 79 covers the synthesis, testing and
recording of the medicinal properties of natural products, providing cutting-edge accounts of …
recording of the medicinal properties of natural products, providing cutting-edge accounts of …
Dammarane-type leads panaxadiol and protopanaxadiol for drug discovery: biological activity and structural modification
M Wang, H Li, W Liu, H Cao, X Hu, X Gao, F Xu… - European Journal of …, 2020 - Elsevier
Based on the definite therapeutic benefits, such as neuroprotective, cardioprotective,
anticancer, anti-diabetic and so on, the Panax genus which contains many valuable plants …
anticancer, anti-diabetic and so on, the Panax genus which contains many valuable plants …
A quinquennial review on recent advancements and developments in search of anti-malarial agents
TM Dhameliya, D Kathuria, TM Patel… - Current Topics in …, 2023 - ingentaconnect.com
Malaria has been a major parasitic disease in tropical and subtropical regions and is
estimated to kill between one and two million people (mainly children) every year. Novel anti …
estimated to kill between one and two million people (mainly children) every year. Novel anti …