Insights into the role of senescence in tumor dormancy: mechanisms and applications

VJ DeLuca, T Saleh - Cancer and Metastasis Reviews, 2023 - Springer
One of the most formidable challenges in oncology and tumor biology research is to provide
an accurate understanding of tumor dormancy mechanisms. Dormancy refers to the ability of …

Autophagy and senescence in cancer therapy

NH Patel, S Bloukh, E Alwohosh, A Alhesa… - Advances in cancer …, 2021 - Elsevier
Tumor cells can undergo diverse responses to cancer therapy. While apoptosis represents
the most desirable outcome, tumor cells can alternatively undergo autophagy and …

[HTML][HTML] Pattern of failure analysis in metastatic EGFR-mutant lung cancer treated with tyrosine kinase inhibitors to identify candidates for consolidation stereotactic …

H Al-Halabi, K Sayegh, SR Digamurthy… - Journal of Thoracic …, 2015 - Elsevier
Introduction The role of stereotactic body radiation therapy (SBRT) in patients with metastatic
lung cancer harboring epidermal growth factor receptor (EGFR) mutations is not defined. We …

Emerging treatment for advanced lung cancer with EGFR mutation

C Inal, E Yilmaz, B Piperdi, R Perez-Soler… - Expert Opinion on …, 2015 - Taylor & Francis
Introduction: Lung cancer is the leading cause of cancer-related death worldwide. It is
usually diagnosed at advanced stage for which platinum-based chemotherapy had been the …

Étude des mécanismes de résistance aux inhibiteurs de PARP dans le cancer de la prostate

M Cahuzac - 2022 - papyrus.bib.umontreal.ca
Le cancer de la prostate (CP) est le cancer le plus diagnostiqué chez les hommes en
Amérique du Nord. Même si les méthodes de détection et les traitements s' améliorent au fil …

The Role of Autophagy and Senescence in the Responses of Non-Small Cell Lung Cancer Cells to Chemotherapy and Radiation

NH Patel - 2021 - scholarscompass.vcu.edu
Cancer-associated deaths account for the second-highest mortality rates in the United
States. Primary modalities of treatment often include surgery, radiation, and chemotherapy …

Rôle du stress hypoxique dans la régulation de la réponse immunitaire anti-tumorale des lymphocytes" Natural Killer"

G Berchem - 2014 - theses.hal.science
Le microenvironnement tumoral, et notamment le stress hypoxique, joue un rôle
immunosuppressif permettant l'échappement des cellules tumorales à la surveillance du …