Neutropenia: causes and consequences
L Boxer, DC Dale - Seminars in hematology, 2002 - Elsevier
Neutrophils play a critical role in the acute inflammatory response and host-defenses
against bacterial infections. Neutropenia, a deficiency of these cells, predisposes to …
against bacterial infections. Neutropenia, a deficiency of these cells, predisposes to …
[HTML][HTML] Adult human bone marrow–derived mesenchymal progenitor cells are capable of adhesion-independent survival and expansion
D Baksh, JE Davies, PW Zandstra - Experimental hematology, 2003 - Elsevier
Overview. We show the existence of adult human mesenchymal progenitor cells (hMPCs)
that can proliferate, in a cytokine-dependent manner, as individual cells in stirred …
that can proliferate, in a cytokine-dependent manner, as individual cells in stirred …
The role of novel and known extracellular matrix and adhesion molecules in the homeostatic and regenerative bone marrow microenvironment
S Klamer, C Voermans - Cell adhesion & migration, 2014 - Taylor & Francis
Maintenance of haematopoietic stem cells and differentiation of committed progenitors
occurs in highly specialized niches. The interactions of haematopoietic stem and progenitor …
occurs in highly specialized niches. The interactions of haematopoietic stem and progenitor …
[HTML][HTML] The glycoprotein IIb molecule is expressed on early murine hematopoietic progenitors and regulates their numbers in sites of hematopoiesis
NR Emambokus, J Frampton - Immunity, 2003 - cell.com
The α integrin GPIIb is a marker of hematopoietic progenitors. Using a marking strategy
based on Cre-loxP technology to trace the fate of GPIIb-expressing cells, we show that GPIIb …
based on Cre-loxP technology to trace the fate of GPIIb-expressing cells, we show that GPIIb …
[HTML][HTML] Stem cell regulation via dynamic interactions of the nervous and immune systems with the microenvironment
A Spiegel, A Kalinkovich, S Shivtiel, O Kollet, T Lapidot - Cell stem cell, 2008 - cell.com
Physiological interactions between the nervous and immune systems with components of
the local microenvironment are needed to maintain homeostasis throughout the body …
the local microenvironment are needed to maintain homeostasis throughout the body …
[HTML][HTML] Effects of mesenchymal stem cell derivatives on hematopoiesis and hematopoietic stem cells
S Aqmasheh, P Akbarzadehlaleh… - Advanced …, 2017 - ncbi.nlm.nih.gov
Hematopoiesis is a balance among quiescence, self-renewal, proliferation, and
differentiation, which is believed to be firmly adjusted through interactions between …
differentiation, which is believed to be firmly adjusted through interactions between …
[HTML][HTML] Cytokine requirements differ for stroma and embryoid body-mediated hematopoiesis from human embryonic stem cells
X Tian, JK Morris, JL Linehan, DS Kaufman - Experimental hematology, 2004 - Elsevier
OBJECTIVE: Human embryonic stem (ES) cells can be induced to differentiate into
hematopoietic lineages either by stromal cell coculture or by formation of embryoid bodies …
hematopoietic lineages either by stromal cell coculture or by formation of embryoid bodies …
Cell surface glycan–lectin interactions in tumor metastasis
NDS Rambaruth, MV Dwek - Acta histochemica, 2011 - Elsevier
The development of secondary cancers, metastases, requires that a multitude of events are
completed in an ordered and sequential manner. This review focuses on the role of cell …
completed in an ordered and sequential manner. This review focuses on the role of cell …
[HTML][HTML] Outside-in integrin signalling regulates haematopoietic stem cell function via Periostin-Itgav axis
S Khurana, S Schouteden, JK Manesia… - Nature …, 2016 - nature.com
Integrins play an important role in haematopoietic stem cell (HSC) maintenance in the bone
marrow niche. Here, we demonstrate that Periostin (Postn) via interaction with Integrin-αv …
marrow niche. Here, we demonstrate that Periostin (Postn) via interaction with Integrin-αv …
Hematopoietic support capacity of mesenchymal stem cells: biology and clinical potential
GR Fajardo-Orduña, H Mayani… - Archives of medical …, 2015 - Elsevier
Mesenchymal stem cells (MSCs) play an important role in the physiology and homeostasis
of the hematopoietic system. Because MSCs generate most of the stromal cells present in …
of the hematopoietic system. Because MSCs generate most of the stromal cells present in …