Fabrication of biofunctionalized, cell-laden macroporous 3D PEG hydrogels as bone marrow analogs for the cultivation of human hematopoietic stem and progenitor …
L Rödling, A Raic, C Lee-Thedieck - Biomimetics and Stem Cells: Methods …, 2014 - Springer
In vitro proliferation of hematopoietic stem cells (HSCs) is yet an unresolved challenge.
Found in the bone marrow, HSCs can undergo self-renewing cell division and thereby …
Found in the bone marrow, HSCs can undergo self-renewing cell division and thereby …
Regulation of lymphoid and myeloid leukemic cell survival: role of stromal cell adhesion molecules
BM Hall, LF Gibson - Leukemia & lymphoma, 2004 - Taylor & Francis
Several laboratories have documented the necessity for direct contact of lymphoid and
myeloid leukemic cells with bone marrow stromal cells for optimal survival. Subsequent …
myeloid leukemic cells with bone marrow stromal cells for optimal survival. Subsequent …
[HTML][HTML] G-CSF increases the expression of VCAM-1 on stromal cells promoting the adhesion of CD34+ hematopoietic cells: studies under flow conditions
B Fuste, G Escolar, P Marin, R Mazzara… - Experimental …, 2004 - Elsevier
OBJECTIVE AND METHODS: The knowledge of the mechanisms underlying the adhesive
processes that lead to homing and/or mobilization of hematopoietic progenitor cells, and the …
processes that lead to homing and/or mobilization of hematopoietic progenitor cells, and the …
Serum CD44 levels predict survival in patients with low-risk myelodysplastic syndromes
J Loeffler-Ragg, U Germing, WR Sperr… - Critical reviews in …, 2011 - Elsevier
Myelodysplastic syndromes (MDS) represent a heterogeneous group of clonal
hematopoietic stem cell disorders that are preferentially diagnosed in the elderly. Aberrant …
hematopoietic stem cell disorders that are preferentially diagnosed in the elderly. Aberrant …
The effect of mild agitation on in vitro erythroid development
D Boehm, WG Murphy, M Al-Rubeai - Journal of immunological methods, 2010 - Elsevier
The cultivation of erythroid cells at large scale would have to be performed in suitable
bioreactors which would most likely employ some mode of agitation to ensure optimal mass …
bioreactors which would most likely employ some mode of agitation to ensure optimal mass …
Polychromatic flow cytometry analysis of CD34+ hematopoietic stem cells in cryopreserved early preterm human cord blood samples
F D'Alessio, P Mirabelli, M Gorrese, G Scalia… - Cytometry Part …, 2011 - Wiley Online Library
During the last decades, extended characterizations were performed of human full‐term
cord blood (hTCB) cells, but little information is available on human early preterm cord blood …
cord blood (hTCB) cells, but little information is available on human early preterm cord blood …
Adhesion structures in leukemia cells and their regulation by Src family kinases
P Röselová, A Obr, A Holoubek… - Cell Adhesion & …, 2018 - Taylor & Francis
Interaction of leukemia blasts with the bone marrow extracellular matrix often results in
protection of leukemia cells from chemotherapy and in persistence of the residual disease …
protection of leukemia cells from chemotherapy and in persistence of the residual disease …
Niche-mediated integrin signaling supports steady-state hematopoiesis in the spleen
SH Mehatre, IM Roy, A Biswas, D Prit… - The Journal of …, 2021 - journals.aai.org
Outside-in integrin signaling regulates cell fate decisions in a variety of cell types, including
hematopoietic stem cells (HSCs). Our earlier published studies showed that interruption of …
hematopoietic stem cells (HSCs). Our earlier published studies showed that interruption of …
Cord blood transplantation in adult patients
W Tse, MJ Laughlin - Cytotherapy, 2005 - Taylor & Francis
Early clinical reports outlining outcomes for primarily pediatric patients undergoing UCB
transplantation point to delayed time to hematopoietic recovery and favorable incidence and …
transplantation point to delayed time to hematopoietic recovery and favorable incidence and …