Human papillomaviruses-associated cancers: an update of current knowledge

E Pešut, A Đukić, L Lulić, J Skelin, I Šimić… - Viruses, 2021 - mdpi.com
Human papillomaviruses (HPVs), which are small, double-stranded, circular DNA viruses
infecting human epithelial cells, are associated with various benign and malignant lesions of …

Molecular markers for cervical cancer screening

C Güzel, J van Sten-van't Hoff… - Expert review of …, 2021 - Taylor & Francis
This review gives an overview of current screening practices for cervical cancer. In the
introduction, we will cover approaches of population screening focusing on high-risk Human …

Accuracy of HPV E6/E7 oncoprotein tests to detect high-grade cervical lesions: a systematic literature review and meta-analysis

L Downham, I Jaafar, ML Rol, V Nyawira Nyaga… - British Journal of …, 2024 - nature.com
Background Cervical carcinogenesis is mediated by the HPV-E6 and E7 oncoproteins,
considered as biomarkers usable in managing screen-positive women. Methods We …

Multicentric study of cervical cancer screening with human papillomavirus testing and assessment of triage methods in Latin America: the ESTAMPA screening study …

M Almonte, R Murillo, GI Sánchez, P González… - BMJ open, 2020 - bmjopen.bmj.com
Introduction Human papillomavirus (HPV) testing is replacing cytology in primary screening.
Its limited specificity demands using a second (triage) test to better identify women at high …

Molecular triaging options for women testing HPV positive with self-collected samples

K Taghavi, F Zhao, L Downham, A Baena… - Frontiers in …, 2023 - frontiersin.org
We review developments in molecular triaging options for women who test positive for high-
risk human papillomavirus (hrHPV) on self-collected samples in the context of cervical …

Value of high‑risk human papillomavirus detection combined with colposcopy in the diagnosis of cervical cancer and precancerous lesions

P Wang, D Gao, X Yu, G Zhu - Oncology Letters, 2024 - spandidos-publications.com
In the present study, the diagnostic value of high risk‑human papillomavirus (HR‑HPV)
combined with colposcopy for the detection of cervical cancer and precancerous lesions …

Field experience with the 8‐HPV‐type oncoprotein test for cervical cancer screening among HPV‐positive women living with and without HIV in LMICs

L Downham, ML Rol, M Forestier… - … Journal of Cancer, 2024 - Wiley Online Library
Overexpression of HPV‐oncoproteins E6 and E7 is necessary for HPV‐driven cervical
carcinogenesis. Hence, these oncoproteins are promising disease‐specific biomarkers. We …

Performance of cervical screening a decade following HPV vaccination: the Costa Rica Vaccine Trial

SY Hu, AR Kreimer, C Porras, D Guillén… - Journal Of The …, 2022 - academic.oup.com
Background We investigated the impact of human papillomavirus (HPV) vaccination on the
performance of cytology-based and HPV-based screening for detection of cervical …

Development of a sensitive and specific nanoparticle‐assisted PCR assay for detecting HPV‐16 and HPV‐18 DNA

X Ma, Y Li, R Liu, W Wei, C Ding - Journal of Medical Virology, 2020 - Wiley Online Library
Carcinoma precursor lesion caused by persistent infection of human papillomavirus (HPV)
types 16 and 18 is known as a principal inducer of cervical cancer. Therefore, rapid and …

A dual-signal electrochemical immunosensor for the detection of HPV16 E6 oncoprotein based on PdBP dendritic ternary nanospheres and MBSi-Chi …

T Wen, C Xia, Q Yu, Y Yu, S Li, C Zhou, K Sun, S Yue - Analyst, 2022 - pubs.rsc.org
Cervical cancer is a common cancer in women. HPV16 E6 oncoprotein is a reliable
biomarker for cervical cancer. Although there are other methods for detecting E6 …