Diffuse glioma growth: a guerilla war

A Claes, AJ Idema, P Wesseling - Acta neuropathologica, 2007 - Springer
In contrast to almost all other brain tumors, diffuse gliomas infiltrate extensively in the
neuropil. This growth pattern is a major factor in therapeutic failure. Diffuse infiltrative glioma …

'Pseudopalisading'necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis

Y Rong, DL Durden, EG Van Meir… - … of Neuropathology & …, 2006 - academic.oup.com
Glioblastoma (GBM) is a highly malignant, rapidly progressive astrocytoma that is
distinguished pathologically from lower grade tumors by necrosis and microvascular …

FDA drug approval summary: bevacizumab (Avastin®) as treatment of recurrent glioblastoma multiforme

MH Cohen, YL Shen, P Keegan, R Pazdur - The oncologist, 2009 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to: Discuss
and compare currently approved drugs for treatment of glioblastoma multiforme (GBM) and …

Identification of noninvasive imaging surrogates for brain tumor gene-expression modules

M Diehn, C Nardini, DS Wang… - Proceedings of the …, 2008 - National Acad Sciences
Glioblastoma multiforme (GBM) is the most common and lethal primary brain tumor in adults.
We combined neuroimaging and DNA microarray analysis to create a multidimensional map …

Modulating Nanozyme‐Based Nanomachines via Microenvironmental Feedback for Differential Photothermal Therapy of Orthotopic Gliomas

N Yin, Y Wang, Y Huang, Y Cao, L Jin, J Liu… - Advanced …, 2023 - Wiley Online Library
Gliomas are common and refractory primary tumors closely associated with the fine
structures of the brain. Photothermal therapy (PTT) has recently shown promise as an …

Assessing the predictability of IDH mutation and MGMT methylation status in glioma patients using relaxation-compensated multipool CEST MRI at 7.0 T

D Paech, J Windschuh, J Oberhollenzer… - Neuro …, 2018 - academic.oup.com
Background Early identification of prognostic superior characteristics in glioma patients such
as isocitrate dehydrogenase (IDH) mutation and O6-methylguanine-DNA-methyltransferase …

Clinical applications of magnetic resonance spectroscopy in brain tumors: from diagnosis to treatment

BD Weinberg, M Kuruva, H Shim… - Radiologic …, 2021 - radiologic.theclinics.com
Magnetic resonance spectroscopy (MRS) is a technique that combines the ability of nuclear
magnetic resonance (NMR) to differentiate molecules with the imaging features of …

A biodegradable nanocapsule for through-skull NIR-II fluorescence imaging/magnetic resonance imaging and selectively enhanced radio-chemotherapy for orthotopic …

N Yin, Y Wang, Y Cao, Y Huang, L Jin, S Zhang, J Liu… - Nano Today, 2022 - Elsevier
Abstract Treatment of glioblastoma (GBM) remains a significant challenge in clinic because
of the difficulty in discriminating the tumor margins in surgical resection, and the low blood …

A multi-sequence and habitat-based MRI radiomics signature for preoperative prediction of MGMT promoter methylation in astrocytomas with prognostic implication

J Wei, G Yang, X Hao, D Gu, Y Tan, X Wang, D Dong… - European …, 2019 - Springer
Objectives Oxygen 6-methylguanine-DNA methyltransferase (MGMT) promoter methylation
is a significant prognostic biomarker in astrocytomas, especially for temozolomide (TMZ) …

Brain tumor segmentation of multi-modality MR images via triple intersecting U-Nets

J Zhang, J Zeng, P Qin, L Zhao - Neurocomputing, 2021 - Elsevier
In this paper, we propose a triple intersecting U-Nets (TIU-Nets) for brain glioma
segmentation. First, the proposed TIU-Nets is composed of binary-class segmentation U-Net …