Highlights•The FIGO 'PALM COEIN'classification of AUB is considered in this
review•Mechanisms by which fibroids contribute to AUB are elucidated.•A structured …

Uterine fibroids (also known as leiomyomas or myomas) are the most common form of
benign uterine tumors. Clinical presentations include abnormal bleeding, pelvic masses …

Uterine fibroids (leiomyomas) are noncancerous growths that can have deleterious effects
on the health and quality of life for millions of women. Attempts to better understand the …

Uterine fibroids are the most common benign uterine tumors. This review examines the
different management strategies, involving mainly surgery, and evaluates them in the light of …

The recent shift in focus from hormones to fibroid stem cells and genetic aberrations should
lead not only to a deeper understanding of the specific cause of fibroids, but also to the …

Uterine fibroid (UF) driver mutations in Mediator complex subunit 12 (MED12) trigger
genomic instability and tumor development through unknown mechanisms. Herein, we show …

Leiomyomas, or uterine fibroids as they are commonly known, are mostly seen in women of
reproductive age. However, they can go undetected in most women, and approximately 25 …

Highlights•Medical management should be considered as an alternative to surgery in the
management of fibroids.•Selection of medical management should be based on a patient's …

ABSTRACT Introduction Uterine fibroids (UFs) are the most common benign tumor arising
from myometrium of reproductive age women, with significant financial burden estimated in …

This study was designed to examine the expression and cellular distribution of homeobox
(HOX) genes (HOXA10 and HOXA 11) and cell adhesion molecules (E-cadherin, N …