Liposomes in cancer therapy: how did we start and where are we now

MD Fulton, W Najahi-Missaoui - International Journal of Molecular …, 2023 - mdpi.com
Since their first discovery in the 1960s by Alec Bangham, liposomes have been shown to be
effective drug delivery systems for treating various cancers. Several liposome-based …

Liposomes for the treatment of brain cancer—A review

R Raju, WH Abuwatfa, WG Pitt, GA Husseini - Pharmaceuticals, 2023 - mdpi.com
Due to their biocompatibility, non-toxicity, and surface-conjugation capabilities, liposomes
are effective nanocarriers that can encapsulate chemotherapeutic drugs and facilitate …

A new theranostic pH-responsive niosome formulation for doxorubicin delivery and bio-imaging against breast cancer

S Saharkhiz, A Zarepour, A Zarrabi - International Journal of Pharmaceutics, 2023 - Elsevier
As one of the newest generations of nanoplatforms, smart nanotheranostics have attracted
signifivant attentions for medical applications, especially in oncology and cancer treatment …

Intranasal delivery of liposomes to glioblastoma by photostimulation of the lymphatic system

O Semyachkina-Glushkovskaya, A Shirokov, I Blokhina… - Pharmaceutics, 2022 - mdpi.com
The blood–brain barrier (BBB) limits the delivery of majority of cancer drugs and thereby
complicates brain tumor treatment. The nasal-brain-lymphatic system is discussed as a …

Liposomes-based drug delivery systems of anti-biofilm agents to combat bacterial biofilm formation

Z Makhlouf, AA Ali, MH Al-Sayah - Antibiotics, 2023 - mdpi.com
All currently approved antibiotics are being met by some degree of resistance by the
bacteria they target. Biofilm formation is one of the crucial enablers of bacterial resistance …

Advanced drug delivery platforms for the treatment of oral pathogens

SE Alavi, A Raza, M Gholami, M Giles, R Al-Sammak… - Pharmaceutics, 2022 - mdpi.com
The oral cavity is a complex ecosystem accommodating various microorganisms (eg,
bacteria and fungi). Various factors, such as diet change and poor oral hygiene, can change …

Resorbable GBR scaffolds in oral and maxillofacial tissue engineering: design, fabrication, and applications

SE Alavi, M Gholami, HE Shahmabadi… - Journal of Clinical …, 2023 - mdpi.com
Guided bone regeneration (GBR) is a promising technique in bone tissue engineering that
aims to replace lost or injured bone using resorbable scaffolds. The promotion of osteoblast …

Two-Step Targeted Drug Delivery via Proteinaceous Barnase-Barstar Interface and Doxorubicin-Loaded Nano-PLGA Outperforms One-Step Strategy for Targeted …

EN Komedchikova, OA Kolesnikova, ED Tereshina… - Pharmaceutics, 2022 - mdpi.com
Nanoparticle-based chemotherapy is considered to be an effective approach to cancer
diagnostics and therapy in modern biomedicine. However, efficient tumor targeting remains …

A topical gel nanoformulation of amphotericin B (AmB) for the treatment of cutaneous leishmaniasis (CL)

R Boshrouyeh, S Amari… - Journal of Sol-Gel …, 2023 - Springer
This study aimed to improve the water solubility and cutaneous permeability of Amphotericin
B (AmB) for the topical treatment of Leishmania major-induced cutaneous leishmaniasis …

Multiple therapeutic approaches of glioblastoma multiforme: from terminal to therapy

S Kumari, R Gupta, RK Ambasta, P Kumar - Biochimica et Biophysica Acta …, 2023 - Elsevier
Glioblastoma multiforme (GBM) is an aggressive brain cancer showing poor prognosis.
Currently, treatment methods of GBM are limited with adverse outcomes and low survival …