[HTML][HTML] Exploring novel therapeutic targets in the common pathogenic factors in migraine and neuropathic pain
J Tajti, D Szok, A Csáti, Á Szabó, M Tanaka… - International Journal of …, 2023 - mdpi.com
Migraine and neuropathic pain (NP) are both painful, disabling, chronic conditions which
exhibit some symptom similarities and are thus considered to share a common etiology. The …
exhibit some symptom similarities and are thus considered to share a common etiology. The …
[HTML][HTML] From CGRP to PACAP, VIP, and Beyond: Unraveling the Next Chapters in Migraine Treatment
Migraine is a neurovascular disorder that can be debilitating for individuals and society.
Current research focuses on finding effective analgesics and management strategies for …
Current research focuses on finding effective analgesics and management strategies for …
[HTML][HTML] Clinical evaluation of super-responders vs. non-responders to CGRP (-receptor) monoclonal antibodies: a real-world experience
B Raffaelli, M Fitzek, LH Overeem, E Storch… - The Journal of …, 2023 - Springer
Background Clinical trials and real-world studies revealed a spectrum of response to CGRP
(-receptor) monoclonal antibodies (mAbs) in migraine prophylaxis, ranging from no effect at …
(-receptor) monoclonal antibodies (mAbs) in migraine prophylaxis, ranging from no effect at …
[HTML][HTML] Biomarkers of migraine: an integrated evaluation of preclinical and clinical findings
C Demartini, M Francavilla, AM Zanaboni… - International journal of …, 2023 - mdpi.com
In recent years, numerous efforts have been made to identify reliable biomarkers useful in
migraine diagnosis and progression or associated with the response to a specific treatment …
migraine diagnosis and progression or associated with the response to a specific treatment …
[HTML][HTML] The role of microRNA in migraine: a systemic literature review
O Grodzka, S Słyk, I Domitrz - Cellular and Molecular Neurobiology, 2023 - Springer
Migraine is a common primary headache disorder, affecting about 14% of the population.
Importantly, it was indicated as the second cause of disability globally and the leading cause …
Importantly, it was indicated as the second cause of disability globally and the leading cause …
[HTML][HTML] Characterization of the biochemical and behavioral effects of cannabidiol: implications for migraine
R Greco, M Francavilla, C Demartini… - The journal of headache …, 2023 - Springer
Cannabidiol (CBD) is the main pharmacologically active phytocannabinoid. CBD exerts an
analgesic effect in several pain models, does not have side effects and has low toxicity. The …
analgesic effect in several pain models, does not have side effects and has low toxicity. The …
[HTML][HTML] Calcitonin Gene-Related Peptide-Mediated Trigeminal Ganglionitis: The Biomolecular Link between Temporomandibular Disorders and Chronic Headaches
L Sangalli, B Eli, S Mehrotra, S Sabagh… - International Journal of …, 2023 - mdpi.com
A bidirectional causal relationship has been established between temporomandibular
disorders (TMDs) and chronic headaches. Recent advances in the neurobiology of chronic …
disorders (TMDs) and chronic headaches. Recent advances in the neurobiology of chronic …
Cellular and Molecular Roles of Immune Cells in the Gut-Brain Axis in Migraine
Y Zhou, M Pang, Y Ma, L Lu, J Zhang, P Wang… - Molecular …, 2024 - Springer
Migraine is a complex and multi-system dysfunction. The realization of its pathophysiology
and diagnosis is developing rapidly. Migraine has been linked to gastrointestinal disorders …
and diagnosis is developing rapidly. Migraine has been linked to gastrointestinal disorders …
[HTML][HTML] Calcitonin receptor, calcitonin gene-related peptide and amylin distribution in C1/2 dorsal root ganglia
Background The upper cervical dorsal root ganglia (DRG) are important for the transmission
of sensory information associated with the back of the head and neck, contributing to head …
of sensory information associated with the back of the head and neck, contributing to head …
Fenofibrate ameliorates nitroglycerin-induced migraine in rats: Role of CGRP/p-CREB/P2X3 and NGF/PKC/ASIC3 signaling pathways
Migraine, a debilitating neurological condition, significantly affects patients' quality of life.
Fenofibrate, a peroxisome proliferator-activated receptor alpha (PPAR-α) agonist approved …
Fenofibrate, a peroxisome proliferator-activated receptor alpha (PPAR-α) agonist approved …