Classical monocyte ontogeny dictates their functions and fates as tissue macrophages

S Trzebanski, JS Kim, N Larossi, A Raanan… - Immunity, 2024 - cell.com
Classical monocytes (CMs) are ephemeral myeloid immune cells that circulate in the blood.
Emerging evidence suggests that CMs can have distinct ontogeny and originate from either …

Transcription factor C/EBPα is required for the development of Ly6Chi monocytes but not Ly6Clo monocytes

S Kim, J Chen, F Ou, TT Liu, S Jo… - Proceedings of the …, 2024 - National Acad Sciences
Monocytes comprise two major subsets, Ly6Chi classical monocytes and Ly6Clo
nonclassical monocytes. Notch2 signaling in Ly6Chi monocytes triggers transition to Ly6Clo …